Applications and limitations of dendrimers in biomedicine
Biomedicine represents one of the main study areas for dendrimers, which have proven to
be valuable both in diagnostics and therapy, due to their capacity for improving solubility …
be valuable both in diagnostics and therapy, due to their capacity for improving solubility …
Polymer‐based mRNA delivery strategies for advanced therapies
W Yang, L Mixich, E Boonstra… - Advanced Healthcare …, 2023 - Wiley Online Library
Messenger RNA (mRNA)‐based therapies offer great promise for the treatment of a variety
of diseases. In 2020, two FDA approvals of mRNA‐based vaccines have elevated mRNA …
of diseases. In 2020, two FDA approvals of mRNA‐based vaccines have elevated mRNA …
Dendrimers as nanocarriers for nucleic acid and drug delivery in cancer therapy
L Palmerston Mendes, J Pan, VP Torchilin - Molecules, 2017 - mdpi.com
Dendrimers are highly branched polymers with easily modifiable surfaces. This makes them
promising structures for functionalization and also for conjugation with drugs and DNA/RNA …
promising structures for functionalization and also for conjugation with drugs and DNA/RNA …
Dendrimers as pharmaceutical excipients: synthesis, properties, toxicity and biomedical applications
The European Medicines Agency (EMA) and the Current Good Manufacturing Practices
(cGMP) in the United States of America, define excipient as the constituents of the …
(cGMP) in the United States of America, define excipient as the constituents of the …
[HTML][HTML] Emerging innate biological properties of nano-drug delivery systems: A focus on PAMAM dendrimers and their clinical potential
Drug delivery systems or vectors are usually needed to improve the bioavailability and
effectiveness of a drug through improving its pharmacokinetics/pharmacodynamics at an …
effectiveness of a drug through improving its pharmacokinetics/pharmacodynamics at an …
Poly (propylene imine) dendrimer as an emerging polymeric nanocarrier for anticancer drug and gene delivery
V Singh, A Sahebkar, P Kesharwani - European Polymer Journal, 2021 - Elsevier
Dendrimers are well-defined globular macromolecules with multiple polymeric branching
that are amenable to undergo structural modifications. This property makes dendrimers …
that are amenable to undergo structural modifications. This property makes dendrimers …
Dendrimer as nanocarrier for drug delivery
P Kesharwani, K Jain, NK Jain - Progress in Polymer Science, 2014 - Elsevier
Dendrimers are novel three dimensional, hyperbranched globular nanopolymeric
architectures. Attractive features like nanoscopic size, narrow polydispersity index, excellent …
architectures. Attractive features like nanoscopic size, narrow polydispersity index, excellent …
Oral delivery of anticancer drugs: challenges and opportunities
The present report focuses on the various aspects of oral delivery of anticancer drugs. The
significance of oral delivery in cancer therapeutics has been highlighted which principally …
significance of oral delivery in cancer therapeutics has been highlighted which principally …
Dendrimer toxicity: Let's meet the challenge
Dendrimers are well-defined, versatile polymeric architecture with properties resembling
biomolecules. Dendritic polymers emerged as outstanding carrier in modern medicine …
biomolecules. Dendritic polymers emerged as outstanding carrier in modern medicine …
Dendrimer-based drug and imaging conjugates: design considerations for nanomedical applications
AR Menjoge, RM Kannan, DA Tomalia - Drug discovery today, 2010 - Elsevier
Dendrimers are members of a versatile, fourth new class of polymer architecture (ie dendritic
polymers after traditional linear, crosslinked and branched types)[1]. Typically, dendrimers …
polymers after traditional linear, crosslinked and branched types)[1]. Typically, dendrimers …