Molecular imaging and disease theranostics with renal-clearable optical agents

P Cheng, K Pu - Nature Reviews Materials, 2021 - nature.com
Optical imaging in disease diagnosis and treatment benefits from high spatiotemporal
resolution and the availability of numerous optical agents. However, many optical imaging …

Management of fluorescent organic/inorganic nanohybrids for biomedical applications in the NIR-II region

B Li, M Zhao, J Lin, P Huang, X Chen - Chemical Society Reviews, 2022 - pubs.rsc.org
Biomedical fluorescence imaging in the second near-infrared (NIR-II, 100–1700 nm) window
provides great potential for visualizing physiological and pathological processes, owing to …

Molecular optical imaging probes for early diagnosis of drug-induced acute kidney injury

J Huang, J Li, Y Lyu, Q Miao, K Pu - Nature materials, 2019 - nature.com
Drug-induced acute kidney injury (AKI) with a high morbidity and mortality is poorly
diagnosed in hospitals and deficiently evaluated in drug discovery. Here, we report the …

A review of methods for the detection of pathogenic microorganisms

P Rajapaksha, A Elbourne, S Gangadoo, R Brown… - Analyst, 2019 - pubs.rsc.org
The testing and rapid detection of pathogenic organisms is a crucial protocol in the
prevention and identification of crises related to health, safety and wellbeing. Pathogen …

Near-infrared fluorophores for biomedical imaging

G Hong, AL Antaris, H Dai - Nature biomedical engineering, 2017 - nature.com
In vivo near-infrared (NIR) fluorescence imaging is an emerging biomedical imaging
modality for use in both fundamental scientific research and clinical practice. Owing to …

Fully dense UNet for 2-D sparse photoacoustic tomography artifact removal

S Guan, AA Khan, S Sikdar… - IEEE journal of …, 2019 - ieeexplore.ieee.org
Photoacoustic imaging is an emerging imaging modality that is based upon the
photoacoustic effect. In photoacoustic tomography (PAT), the induced acoustic pressure …

Molecular afterglow imaging with bright, biodegradable polymer nanoparticles

Q Miao, C Xie, X Zhen, Y Lyu, H Duan, X Liu… - Nature …, 2017 - nature.com
Afterglow optical agents, which emit light long after cessation of excitation, hold promise for
ultrasensitive in vivo imaging because they eliminate tissue autofluorescence. However …

Multifunctional biohybrid magnetite microrobots for imaging-guided therapy

X Yan, Q Zhou, M Vincent, Y Deng, J Yu, J Xu, T Xu… - Science robotics, 2017 - science.org
Magnetic microrobots and nanorobots can be remotely controlled to propel in complex
biological fluids with high precision by using magnetic fields. Their potential for controlled …

Organic semiconducting agents for deep‐tissue molecular imaging: second near‐infrared fluorescence, self‐luminescence, and photoacoustics

Q Miao, K Pu - Advanced materials, 2018 - Wiley Online Library
Optical imaging has played a pivotal role in biology and medicine, but it faces challenges of
relatively low tissue penetration and poor signal‐to‐background ratio due to light scattering …

Luminescence lifetime imaging based on lanthanide nanoparticles

X Zhu, X Wang, H Zhang… - Angewandte Chemie …, 2022 - Wiley Online Library
Luminescence lifetime imaging has exhibited significant advantages over traditional optical
imaging in terms of precise quantification detection because of the intrinsic stability of …