The cultivated meat industry, also known as cell‐based meat, cultured meat, lab‐grown
meat, or meat alternatives, is a growing field that aims to generate animal tissues ex‐vivo in …

In order to meet the rising demand for biologics and become competitive on the developing
biosimilar market, there is a need for process intensification of biomanufacturing processes …

Chinese hamster ovary (CHO) cells, predominant hosts for recombinant biotherapeutics
production, generate lactate as a major glycolysis by‐product. High lactate levels adversely …

The production of monoclonal antibodies (mAbs) using Chinese Hamster Ovary (CHO) cells
has revolutionized the treatment of numerous diseases, solidifying their position as a …

In this study, we demonstrated a simple strategy for increasing mAb production by enriching
an existing feed with TCA cycle intermediates and precursors. TCA cycle intermediates …

Designing and selecting cell culture media along with their feeding are a key strategy to
maximize culture performance in biopharmaceutical processes. However, the sensitivity of …

Background Autoimmune diseases (ADs) are a category of conditions characterized by
misrecognition of autologous tissues and organs by the immune system, leading to severe …

Technology scale‐up and transfer are a fundamental and critical part of process
development in biomanufacturing. Important bioreactor hydrodynamic characteristics such …

Amino acids, including asparagine, aspartate, glutamine, and glutamate, play important
roles in purine and pyrimidine biosynthesis as well as serve as anaplerotic sources fueling …

Technology scale-up and transfer are a fundamental and critical part of process
development in biomanufacturing. Important bioreactor hydrodynamic characteristics such …