Hypertension and hyperhomocysteinemia as modifiable risk factors for Alzheimer's disease and dementia: New evidence, potential therapeutic strategies, and …

A Carey, S Fossati - Alzheimer's & Dementia, 2023 - Wiley Online Library
This review summarizes recent evidence on how mid‐life hypertension,
hyperhomocysteinemia (HHcy) and blood pressure variability, as well as late‐life …

Heart failure-induced cognitive dysfunction is mediated by intracellular Ca2+ leak through ryanodine receptor type 2

H Dridi, Y Liu, S Reiken, X Liu, EK Argyrousi… - Nature …, 2023 - nature.com
Cognitive dysfunction (CD) in heart failure (HF) adversely affects treatment compliance and
quality of life. Although ryanodine receptor type 2 (RyR2) has been linked to cardiac muscle …

Cognitive impairment in heart failure: landscape, challenges, and future directions

M Yang, D Sun, Y Wang, M Yan, J Zheng… - Frontiers in …, 2022 - frontiersin.org
Heart failure (HF) is a major global healthcare problem accounting for substantial
deterioration of prognosis. As a complex clinical syndrome, HF often coexists with multi …

Blood–brain barrier permeable β-blockers linked to lower risk of Alzheimer's disease in hypertension

EE Beaman, AN Bonde, SMU Larsen, B Ozenne… - Brain, 2023 - academic.oup.com
Alzheimer's disease is a neurodegenerative disorder in which the pathological accumulation
of amyloid-β and tau begins years before symptom onset. Emerging evidence suggests that …

Dementia prevention in clinical practice

K Niotis, K Akiyoshi, C Carlton… - Seminars in …, 2022 - thieme-connect.com
Over 55 million people globally are living with dementia and, by 2050, this number is
projected to increase to 131 million. This poses immeasurable challenges for patients and …

The Main Risk Factors in Type 2 Diabetes for Cognitive Dysfunction, Depression, and Psychosocial Problems: A Systematic Review

M Randväli, T Toomsoo, J Šteinmiller - Diabetology, 2024 - mdpi.com
The aim of this study is to analyze the risk factors that lead to cognitive impairment,
depression, and psychosocial problems in type 2 diabetes and discern what aspects they …

[HTML][HTML] A correlative relationship between heart failure and cognitive impairment: a narrative review

MS Park, EJ Kim - Journal of Korean Medical Science, 2023 - ncbi.nlm.nih.gov
Heart failure (HF) is a chronic condition affecting millions of people worldwide. While the
cardinal manifestations of HF are related to the cardiovascular system, it has become …

Alzheimer's disease risk reduction in clinical practice: a priority in the emerging field of preventive neurology

K Niotis, C Saperia, N Saif, C Carlton… - Nature Mental …, 2024 - nature.com
Alzheimer's disease is increasing in prevalence disproportionately to longevity, placing
enormous burden on individuals, families, healthcare systems and the economy …

Acute Myocardial Infarction and Risk of Cognitive Impairment and Dementia: A Review

EHE Thong, EJW Quek, JH Loo, CY Yun, YN Teo… - Biology, 2023 - mdpi.com
Simple Summary Cognitive impairment (CI) and dementia are common in patients with heart
attacks, and both share common cardiovascular risk factors. In our ageing population, the …

Atrial fibrillation and cognitive impairment: an associated burden or burden by association?

TA Manolis, AA Manolis, EJ Apostolopoulos… - …, 2020 - journals.sagepub.com
Growing evidence suggests that atrial fibrillation (AF), in addition to its thromboembolic risk,
is a risk factor for cognitive impairment (CI) via several pathways and mechanisms, further …