[HTML][HTML] Breaking therapy resistance: an update on oncolytic newcastle disease virus for improvements of cancer therapy

V Schirrmacher, S van Gool, W Stuecker - Biomedicines, 2019 - mdpi.com
Resistance to therapy is a major obstacle to cancer treatment. It may exist from the
beginning, or it may develop during therapy. The review focusses on oncolytic Newcastle …

[HTML][HTML] Oncolytic viruses for triple negative breast cancer and beyond

S Jin, Q Wang, H Wu, D Pang, S Xu - Biomarker Research, 2021 - Springer
Biological therapy is considered an alternative treatment capable of eliciting the same
effects on tumors as surgery, radiotherapy, and chemotherapy. As a major player in …

[HTML][HTML] Development of molecular mechanisms and their application on oncolytic Newcastle disease virus in cancer therapy

F Huang, C Dai, Y Zhang, Y Zhao, Y Wang… - Frontiers in Molecular …, 2022 - frontiersin.org
Cancer is caused by the destruction or mutation of cellular genetic materials induced by
environmental or genetic factors. It is defined by uncontrolled cell proliferation and …

[HTML][HTML] Inhibition of tumor growth and metastasis by Newcastle disease virus strain P05 in a breast cancer mouse model

OA Ortega-Rivera, P Gallegos-Alcalá… - Journal of Breast …, 2023 - ncbi.nlm.nih.gov
Purpose Conventional therapies and surgery remain the standard treatment for breast
cancer. However, combating the eventual development of metastasis is still a challenge …

Current advances in microbial-based cancer therapies

A Shahbaz, T Mahmood, MU Javed, BH Abbasi - Medical Oncology, 2023 - Springer
Microbes have an immense metabolic capability and can adapt to a wide variety of
environments; as a result, they share complicated relationships with cancer. The goal of …

[HTML][HTML] Molecular cytogenomic characterization of the murine breast cancer cell lines C-127I, EMT6/P and TA3 Hauschka

S Azawi, T Liehr, M Rincic, M Manferrari - International journal of …, 2020 - mdpi.com
Background: To test and introduce effective and less toxic breast cancer (BC) treatment
strategies, animal models, including murine BC cell lines, are considered as perfect …

[HTML][HTML] The role of the tumor microenvironment in developing successful therapeutic and secondary prophylactic breast cancer vaccines

B Gordon, VK Gadi - Vaccines, 2020 - mdpi.com
Breast cancer affects roughly one in eight women over their lifetime and is a leading cause
of cancer-related death in women. While outcomes have improved in recent years …

[HTML][HTML] Oncolytic therapy and gene therapy for cancer: recent advances in antitumor effects of Newcastle disease virus

Z Huang, M Liu, Y Huang - Discovery medicine, 2020 - discoverymedicine.com
Newcastle disease virus (NDV) replicates in the cytoplasm and disintegrates the host
genome or participates in recombination, and has a strong affinity for tumor cells. These …

[HTML][HTML] The NDV-MLS as an Immunotherapeutic Strategy for Breast Cancer: Proof of Concept in Female Companion Dogs with Spontaneous Mammary Cancer

D Sánchez, G Cesarman-Maus, L Romero… - Viruses, 2024 - mdpi.com
The absence of tumor-infiltrating lymphocytes negatively impacts the response to
chemotherapy and prognosis in all subtypes of breast cancer. Therapies that stimulate a …

[HTML][HTML] Cytotoxicity study of the interleukin-12-expressing recombinant Newcastle disease virus strain, rAF-IL12, towards CT26 colon cancer cells in vitro and in vivo

SUFS Najmuddin, ZM Amin, SW Tan, SK Yeap… - Cancer Cell …, 2020 - Springer
Background Oncolytic viruses have emerged as an alternative therapeutic modality for
cancer as they can replicate specifically in tumour cells and induce toxic effects leading to …