Hypoxic pulmonary vasoconstriction
JT Sylvester, LA Shimoda, PI Aaronson… - Physiological …, 2012 - journals.physiology.org
It has been known for more than 60 years, and suspected for over 100, that alveolar hypoxia
causes pulmonary vasoconstriction by means of mechanisms local to the lung. For the last …
causes pulmonary vasoconstriction by means of mechanisms local to the lung. For the last …
Pulmonary vascular wall stiffness: an important contributor to the increased right ventricular afterload with pulmonary hypertension
Z Wang, NC Chesler - Pulmonary circulation, 2011 - journals.sagepub.com
Pulmonary hypertension (PH) is associated with structural and mechanical changes in the
pulmonary vascular bed that increase right ventricular (RV) afterload. These changes …
pulmonary vascular bed that increase right ventricular (RV) afterload. These changes …
[HTML][HTML] Pulmonary circulation at exercise
R Naeije, N Chesler - Comprehensive Physiology, 2012 - ncbi.nlm.nih.gov
The pulmonary circulation is a high flow and low pressure circuit, with an average resistance
of 1 mmHg. min. L− 1 in young adults, increasing to 2.5 mmHg. min. L− 1 over 4–6 decades …
of 1 mmHg. min. L− 1 in young adults, increasing to 2.5 mmHg. min. L− 1 over 4–6 decades …
Biomechanics of the right ventricle in health and disease (2013 Grover Conference series)
R Naeije, S Brimioulle, L Dewachter - Pulmonary circulation, 2014 - journals.sagepub.com
Right ventricular (RV) function is a major determinant of the symptomatology and outcome in
pulmonary hypertension. The normal RV is a thin-walled flow generator able to …
pulmonary hypertension. The normal RV is a thin-walled flow generator able to …
Right ventricular dysfunction in chronic thromboembolic obstruction of the pulmonary artery: a pressure-volume study using the conductance catheter
C McCabe, PA White, SP Hoole… - Journal of applied …, 2014 - journals.physiology.org
Pressure-volume loops describe dynamic ventricular performance, relevant to patients with
and at risk of pulmonary hypertension. We used conductance catheter-derived pressure …
and at risk of pulmonary hypertension. We used conductance catheter-derived pressure …
Doppler echocardiography–derived evidence of pulmonary arterial hypertension in dogs with degenerative mitral valve disease: 86 cases (2001–2005)
FJ Serres, V Chetboul, R Tissier… - Journal of the …, 2006 - Am Vet Med Assoc
Objective—To determine the prevalence of Doppler echocardiography–derived evidence of
pulmonary arterial hypertension (DEE-PAH) in dogs with mitral valve disease (MVD) …
pulmonary arterial hypertension (DEE-PAH) in dogs with mitral valve disease (MVD) …
Cardiac adaptation to chronic high-altitude hypoxia: beneficial and adverse effects
B Ostadal, F Kolar - Respiratory physiology & neurobiology, 2007 - Elsevier
This review deals with the capability of the heart to adapt to chronic hypoxia in animals
exposed to either natural or simulated high altitude. From the broad spectrum of related …
exposed to either natural or simulated high altitude. From the broad spectrum of related …
The principal pathways involved in the in vivo modulation of hypoxic pulmonary vasoconstriction, pulmonary arterial remodelling and pulmonary hypertension
D Kylhammar, G Rådegran - Acta Physiologica, 2017 - Wiley Online Library
Hypoxic pulmonary vasoconstriction (HPV) serves to optimize ventilation–perfusion
matching in focal hypoxia and thereby enhances pulmonary gas exchange. During global …
matching in focal hypoxia and thereby enhances pulmonary gas exchange. During global …
Methods for measuring right ventricular function and hemodynamic coupling with the pulmonary vasculature
A Bellofiore, NC Chesler - Annals of biomedical engineering, 2013 - Springer
The right ventricle (RV) is a pulsatile pump, the efficiency of which depends on proper
hemodynamic coupling with the compliant pulmonary circulation. The RV and pulmonary …
hemodynamic coupling with the compliant pulmonary circulation. The RV and pulmonary …
Effects of levosimendan on acute pulmonary embolism-induced right ventricular failure
F Kerbaul, V Gariboldi, R Giorgi, C Mekkaoui… - Critical care …, 2007 - journals.lww.com
Objective: Repeated episodes of pulmonary embolism can persistently increase pulmonary
arterial pressure and depress right ventricular contractility. We investigated the effects of …
arterial pressure and depress right ventricular contractility. We investigated the effects of …