Synthesis and pharmacological activities of pyrazole derivatives: A review

K Karrouchi, S Radi, Y Ramli, J Taoufik, YN Mabkhot… - Molecules, 2018 - mdpi.com
Pyrazole and its derivatives are considered a pharmacologically important active scaffold
that possesses almost all types of pharmacological activities. The presence of this nucleus in …

Structure-activity relationship (SAR) study and design strategies of nitrogen-containing heterocyclic moieties for their anticancer activities

J Akhtar, AA Khan, Z Ali, R Haider, MS Yar - European journal of medicinal …, 2017 - Elsevier
The present review article offers a detailed account of the design strategies employed for the
synthesis of nitrogen-containing anticancer agents. The results of different studies describe …

The therapeutic voyage of pyrazole and its analogs: a review

MF Khan, MM Alam, G Verma, W Akhtar… - European journal of …, 2016 - Elsevier
Pyrazole, a five membered heteroaromatic ring with two nitrogen atoms is of immense
significance. Presence of this nucleus in the pharmacological agents of diverse therapeutic …

Recent advances in bioactive pyrazoles

ŞG Küçükgüzel, S Şenkardeş - European Journal of Medicinal Chemistry, 2015 - Elsevier
Pyrazole is a five membered and two-nitrogen containing heterocyclic ring. These structures
have been investigated in the development of novel compounds with hypoglycemic …

Current status of pyrazole and its biological activities

MJ Naim, O Alam, F Nawaz, MJ Alam… - Journal of Pharmacy …, 2016 - journals.lww.com
Pyrazole are potent medicinal scaffolds and exhibit a full spectrum of biological activities.
This review throws light on the detailed synthetic approaches which have been applied for …

1, 3, 4‐oxadiazole and its derivatives: A review on recent progress in anticancer activities

A Vaidya, D Pathak, K Shah - Chemical biology & drug design, 2021 - Wiley Online Library
Abstract The 1, 3, 4‐oxadiazole nucleus is a biologically imperative scaffold possesses
numerous biological activities. The broad and potent activity of 1, 3, 4‐oxadiazole and their …

Synthetic approaches and pharmacological activity of 1, 3, 4-oxadiazoles: a review of the literature from 2000–2012

CS De Oliveira, BF Lira, JM Barbosa-Filho… - Molecules, 2012 - mdpi.com
Molecules | Free Full-Text | Synthetic Approaches and Pharmacological Activity of 1,3,4-Oxadiazoles:
A Review of the Literature from 2000–2012 Next Article in Journal Chemical Composition of …

Recent advancement in drug design and discovery of pyrazole biomolecules as cancer and inflammation therapeutics

MJ Alam, O Alam, MJ Naim, F Nawaz, A Manaithiya… - Molecules, 2022 - mdpi.com
Pyrazole, an important pharmacophore and a privileged scaffold of immense significance, is
a five-membered heterocyclic moiety with an extensive therapeutic profile, viz., anti …

Pyrazole scaffold: a remarkable tool in the development of anticancer agents

H Kumar, D Saini, S Jain, N Jain - European Journal of Medicinal Chemistry, 2013 - Elsevier
Pyrazole has been the topic of interest for thousands of researchers across the world
because of its wide spectrum pharmacological activities. Various structural modifications of …

[HTML][HTML] 1, 3, 4-Oxadiazole-containing hybrids as potential anticancer agents: Recent developments, mechanism of action and structure-activity relationships

S Nayak, SL Gaonkar, EA Musad… - Journal of Saudi Chemical …, 2021 - Elsevier
Chemotherapy is an important therapeutic approach for the treatment of cancer. Currently,
many anticancer drugs are available in the market that plays an important role in cancer …