The impaired insulin secretion and increased insulin resistance (or decreased insulin
sensitivity) play a major role in the pathogenesis of all types of diabetes mellitus (DM). It is …

Metabolic reprogramming occurs in tumors to foster cancer cell proliferation, survival and
metastasis, but as well at a systemic level affecting the whole organism, eventually leading …

We evaluated the effects of ketogenic diets (KDs) on body mass (BM), fat mass (FM), fat-free
mass (FFM), body mass index (BMI), and body fat percentage (BFP) compared to non-KDs …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Controversy exists about the maximum amount of protein that can be utilized for lean tissue-
building purposes in a single meal for those involved in regimented resistance training. It …

Insulin resistance contributes to the pathophysiology of diabetes and is a hallmark of
obesity, metabolic syndrome, and many cardiovascular diseases. Therefore, quantifying …

Research in autophagy continues to accelerate, 1 and as a result many new scientists are
entering the field. Accordingly, it is important to establish a standard set of criteria for …

This study was designed to evaluate the effects of enriching an essential amino acid (EAA)
mixture with leucine on muscle protein metabolism in elderly and young individuals. Four (2 …

Diabetes profoundly alters fuel metabolism; both insulin deficiency and insulin resistance
are characterized by inefficient mitochondrial coupling and excessive production of reactive …

We examined the response of net muscle protein synthesis to ingestion of amino acids after
a bout of resistance exercise. A primed, constant infusion of l-[ring-2 H 5] phenylalanine was …