Quinazoline was originally utilized as an anti-tumor treatment, and its various derivatives
can be directly extracted from plants. In recent years, protein kinases (PK) have been well …

Background Cancer treatment using gold (I) complexes is becoming popular. In this study, a
gold (I) N-heterocyclic complex designated as complex 3 was synthesized, its cytotoxicity …

We have synthesized and structurally characterized a new doubly chloro bridged dimeric
copper (II) complex,[Cu2 (μ-Cl) 2 (HL) 2Cl2](1) based on a Schiff base ligand, 5-[(pyridin-2 …

The synthesis, structures and anticancer studies of a series of precious metal complexes
supported by 1-methyl-2-(phenyl) imidazo [1, 5-a] pyridine-2-ylidene (1) have been …

Starting from the proligand 2-[(6-methylpyridin-2-yl)] imidazo [1, 5-a] pyridin-4-ylium
hexafluorophosphate (1· PF6), three new complexes, viz.[Au (1) 2][PF6](2),[1/2AuCl2 …

Lung adenocarcinomas exhibit chemoresistance mostly due to deregulation of nuclear
factor erythroid-derived 2-like 2 (Nrf2). Epigallocatechin gallate (EGCG), was investigated for …

Starting from the proligand 1-methyl-2-pyridin-2-yl-2H-imidazo [1, 5-a] pyridin-4-ylium
chloride (1 HCl), three novel complexes [Ag (1) Cl](2),[Au (1) Cl](3) and [Au (1) Cl3](4) were …

Background/Aims: Cytotoxic effect of attenuated Leishmania on liver cancer cells by
inducing ROS generation. Methods: Spectrophotometric study to analyze cell death and …

Persistence of liver injury alters the internal milieu, promotes deregulation of inflammatory
factors, and leads to dysplastic lesions like fibrosis, cirrhosis to hepatocellular carcinoma …

A series of 22 quinazolines, pyrido [2, 3-d] pyrimidines and their hydroselenite salts were
synthesized with the aim of evaluating in vitro their cytotoxicity against PC-3 cell line and …