The ATG8 family proteins are critical players in autophagy, a cytoprotective process that
mediates degradation of cytosolic cargo. During autophagy, ATG8s conjugate to …

Autophagy is a common name for a number of catabolic processes, which keep the cellular
homeostasis by removing damaged and dysfunctional intracellular components. Impairment …

Aging is associated with many deleterious changes at the cellular level, including the
accumulation of potentially toxic components that can have devastating effects on health. A …

Autophagy is a dynamic circulatory system that occurs in all eukaryotic cells. Cytoplasmic
material is transported to lysosomes for degradation and recovery through autophagy. This …

Eukaryotic cells use post-translational modifications to diversify and dynamically coordinate
the function and properties of protein networks within various cellular processes. For …

Autophagy regulates primary cilia formation, but the underlying mechanism is not fully
understood. In this study, we identify NIMA-related kinase 9 (NEK9) as a GABARAPs …

During autophagy, the ATG8 family proteins have several well-characterized roles in
facilitating early, mid, and late steps of autophagy, including autophagosome expansion …

Autophagy is a recycling mechanism involved in cellular homeostasis with key implications
for health and disease. The conjugation of the ATG8 family proteins, which includes LC3B …

Macroautophagy (hereafter referred to as autophagy) is a conserved process that promotes
cellular homeostasis through the degradation of cytosolic components, also known as cargo …

Rationale: Inflammatory stimuli from the tumor microenvironment play important roles in
cancer progression. However, the mechanism of promotion of cancer metastasis by …