[HTML][HTML] The role of gut dysbiosis in the pathophysiology of neuropsychiatric disorders

N Anand, VR Gorantla, SB Chidambaram - Cells, 2022 - mdpi.com
Mounting evidence shows that the complex gut microbial ecosystem in the human
gastrointestinal (GI) tract regulates the physiology of the central nervous system (CNS) via …

[HTML][HTML] Gut microbiota in anxiety and depression: unveiling the relationships and management options

A Kumar, J Pramanik, N Goyal, D Chauhan… - Pharmaceuticals, 2023 - mdpi.com
The gut microbiota is critical for maintaining human health and the immunological system.
Several neuroscientific studies have shown the significance of microbiota in developing …

[HTML][HTML] “Labels Matter: Is it stress or is it Trauma?”

G Richter-Levin, C Sandi - Translational Psychiatry, 2021 - nature.com
In neuroscience, the term 'Stress' has a negative connotation because of its potential to
trigger or exacerbate psychopathologies. Yet in the face of exposure to stress, the more …

[HTML][HTML] Hypothalamus and post-traumatic stress disorder: a review

P Raise-Abdullahi, M Meamar, AA Vafaei, M Alizadeh… - Brain sciences, 2023 - mdpi.com
Humans have lived in a dynamic environment fraught with potential dangers for thousands
of years. While fear and stress were crucial for the survival of our ancestors, today, they are …

Gut microbiota alterations promote traumatic stress susceptibility associated with p-cresol-induced dopaminergic dysfunctions

S Laudani, SA Torrisi, S Alboni… - Brain, Behavior, and …, 2023 - Elsevier
Mounting evidence suggests a link between gut microbiota abnormalities and post-traumatic
stress disorder (PTSD). However, whether and how the gut microbiota influences PTSD …

[HTML][HTML] BDNF therapeutic mechanisms in neuropsychiatric disorders

AH Bazzari, FH Bazzari - International Journal of Molecular Sciences, 2022 - mdpi.com
Brain-derived neurotrophic factor (BDNF) is the most abundant neurotrophin in the adult
brain and functions as both a primary neurotrophic signal and a neuromodulator. It serves …

[HTML][HTML] Recent advances in the role of miRNAs in post-traumatic stress disorder and traumatic brain injury

Z Zhu, X Huang, M Du, C Wu, J Fu, W Tan, B Wu… - Molecular …, 2023 - nature.com
Post-traumatic stress disorder (PTSD) is usually considered a psychiatric disorder upon
emotional trauma. However, with the rising number of conflicts and traffic accidents around …

Psilocybin facilitates fear extinction in mice by promoting hippocampal neuroplasticity

Y Du, Y Li, X Zhao, Y Yao, B Wang, L Zhang… - Chinese Medical …, 2023 - mednexus.org
Background: Posttraumatic stress disorder (PTSD) and depression are highly comorbid.
Psilocybin exerts substantial therapeutic effects on depression by promoting neuroplasticity …

[HTML][HTML] Significance of GABAA Receptor for Cognitive Function and Hippocampal Pathology

Y Sakimoto, PMT Oo, M Goshima, I Kanehisa… - International Journal of …, 2021 - mdpi.com
The hippocampus is a primary area for contextual memory, known to process spatiotemporal
information within a specific episode. Long-term strengthening of glutamatergic transmission …

[HTML][HTML] Neurotrophins in the neuropathophysiology, course, and complications of obstructive sleep apnea—a narrative review

A Gabryelska, S Turkiewicz, M Ditmer… - International Journal of …, 2023 - mdpi.com
Obstructive sleep apnea (OSA) is a disorder characterized by chronic intermittent hypoxia
and sleep fragmentation due to recurring airway collapse during sleep. It is highly prevalent …