Air pollution, metabolites and respiratory health across the life-course

O Gruzieva, A Jeong, S He, Z Yu… - European …, 2022 - Eur Respiratory Soc
Previous studies have explored the relationships of air pollution and metabolic profiles with
lung function. However, the metabolites linking air pollution and lung function and the …

The role of pericytes in regulation of innate and adaptive immunity

SA Dabravolski, ER Andreeva, II Eremin, AM Markin… - Biomedicines, 2023 - mdpi.com
Pericytes are perivascular multipotent cells wrapping microvascular capillaries, where they
support vasculature functioning, participate in tissue regeneration, and regulate blood flow …

Plasma metabolomic alterations induced by COVID-19 vaccination reveal putative biomarkers reflecting the immune response

I Dagla, A Iliou, D Benaki, E Gikas, E Mikros… - Cells, 2022 - mdpi.com
Vaccination is currently the most effective strategy for the mitigation of the COVID-19
pandemic. mRNA vaccines trigger the immune system to produce neutralizing antibodies …

Pi-Pa-Run-Fei-Tang alleviates lung injury by modulating IL-6/JAK2/STAT3/IL-17 and PI3K/AKT/NF-κB signaling pathway and balancing Th17 and Treg in murine …

XL Jie, ZR Luo, J Yu, ZR Tong, QQ Li, JH Wu… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Pi-Pa-Run-Fei-Tang (PPRFT) is an empirical
TCM prescription for treating asthma. However, the underlying mechanisms of PPRFT in …

S100A4 reprofiles lipid metabolism in mast cells via RAGE and PPAR-γ signaling pathway

M Shihui, Y Shirong, L Jing, H Jingjing… - International …, 2024 - Elsevier
S100A4 is implicated in metabolic reprogramming across various cell types and is known to
propel the progression of numerous diseases including allergies. Nonetheless, the influence …

Predictive models for personalized asthma attacks based on patient's biosignals and environmental factors: a systematic review

ET Alharbi, F Nadeem, A Cherif - BMC Medical Informatics and Decision …, 2021 - Springer
Background Asthma is a chronic disease that exacerbates due to various risk factors,
including the patient's biosignals and environmental conditions. It is affecting on average 7 …

Proline metabolism reprogramming of trained macrophages induced by early respiratory infection combined with allergen sensitization contributes to development of …

H Li, L Ma, W Li, B Zheng, J Wang, S Chen… - Frontiers in …, 2022 - frontiersin.org
Background Infants with respiratory syncytial virus (RSV)-associated bronchiolitis are at
increased risk of childhood asthma. Recent studies demonstrated that certain infections …

Online breath analysis with SESI/HRMS for metabolic signatures in children with allergic asthma

R Weber, B Streckenbach, L Welti, D Inci… - Frontiers in Molecular …, 2023 - frontiersin.org
Introduction: There is a need to improve the diagnosis and management of pediatric asthma.
Breath analysis aims to address this by non-invasively assessing altered metabolism and …

[HTML][HTML] Serum metabolomics reveals metabolomic profile and potential biomarkers in asthma

T Zhu, Y Ma, J Wang, W Xiong, R Mao, B Cui… - Allergy, Asthma & …, 2024 - e-aair.org
Purpose Asthma is a highly heterogeneous disease. Metabolomics plays a pivotal role in the
pathogenesis and development of asthma. The main aims of our study were to explore the …

Extracellular vesicles isolated from hyperuricemia patients might aggravate airway inflammation of COPD via senescence-associated pathway

X Liu, Z Li, Y Zheng, W Wang, P He, K Guan, T Wu… - Journal of …, 2022 - Springer
Backgrounds Chronic obstructive pulmonary disease (COPD) is a major health issue
resulting in significant mortality worldwide. Due to the high heterogeneity and unclear …