The main theories on the pathogenesis of endometriosis

J Lamceva, R Uljanovs, I Strumfa - International journal of molecular …, 2023 - mdpi.com
Endometriosis is a complex disease, which is defined by abnormal growth of endometrial
tissue outside the uterus. It affects about 10% of women of reproductive age all over the …

The endometrial immune environment of women with endometriosis

J Vallvé-Juanico, S Houshdaran… - Human reproduction …, 2019 - academic.oup.com
BACKGROUND Endometriosis, a common oestrogen-dependent inflammatory disorder in
women of reproductive age, is characterized by endometrial-like tissue outside its normal …

The role of the immune system in the development of endometriosis

M Abramiuk, E Grywalska, P Małkowska, O Sierawska… - Cells, 2022 - mdpi.com
Endometriosis is a chronic disease that affects about 10% of women of reproductive age. It
can contribute to pelvic pain, infertility or other conditions such as asthma, cardiovascular …

The association between endometriosis and autoimmune diseases: a systematic review and meta-analysis

N Shigesi, M Kvaskoff, S Kirtley, Q Feng… - Human reproduction …, 2019 - academic.oup.com
BACKGROUND Endometriosis is a chronic gynaecological disorder that affects 2–10% of
women of reproductive age. The aetiology of endometriosis is largely under-explored, yet …

Immunological changes associated with adenomyosis: a systematic review

M Bourdon, P Santulli, M Jeljeli… - Human …, 2021 - academic.oup.com
BACKGROUND Adenomyosis is a benign gynecological disorder associated with
subfertility, pelvic pain and abnormal uterine bleeding that have significant consequences …

Endometriosis: a disease with few direct treatment options

PRC França, ACP Lontra, PD Fernandes - Molecules, 2022 - mdpi.com
Endometriosis is a gynecological condition characterized by the growth of endometrium-like
tissues inside and outside the pelvic cavity. The evolution of the disease can lead to infertility …

A long-acting anti–IL-8 antibody improves inflammation and fibrosis in endometriosis

A Nishimoto-Kakiuchi, I Sato, K Nakano… - Science Translational …, 2023 - science.org
Current pharmacological treatments for endometriosis are limited to hormonal agents that
can relieve pain but cannot cure the disease. Therefore, the development of a disease …

Regulation of inflammation pathways and inflammasome by sex steroid hormones in endometriosis

E García-Gómez, ER Vázquez-Martínez… - Frontiers in …, 2020 - frontiersin.org
Endometriosis is a gynecological disorder characterized by the growth of endometrial tissue
(glands and stroma) outside the uterus, mainly in the peritoneal cavity, ovaries, and …

Immunological basis of the endometriosis: the complement system as a potential therapeutic target

C Agostinis, A Balduit, A Mangogna, G Zito… - Frontiers in …, 2021 - frontiersin.org
Endometriosis (EM) is a chronic disease characterized by the presence and proliferation of
functional endometrial glands and stroma outside the uterine cavity. Ovaries and pelvic …

Infertility in women with systemic autoimmune diseases

J Khizroeva, C Nalli, V Bitsadze, A Lojacono… - Best Practice & …, 2019 - Elsevier
Infertility consists by definition in” failure to achieve a clinical pregnancy after 12 months or
more of regular unprotected intercourse” while the term subfertility means a delay to achieve …