Current trends and challenges in sample preparation for global metabolomics using liquid chromatography–mass spectrometry
D Vuckovic - Analytical and bioanalytical chemistry, 2012 - Springer
The choice of sample-preparation method is extremely important in metabolomic studies
because it affects both the observed metabolite content and biological interpretation of the …
because it affects both the observed metabolite content and biological interpretation of the …
Metabolic characterization of hepatocellular carcinoma using nontargeted tissue metabolomics
Q Huang, Y Tan, P Yin, G Ye, P Gao, X Lu, H Wang… - Cancer research, 2013 - AACR
Hepatocellular carcinoma has a poor prognosis due to its rapid development and early
metastasis. In this report, we characterized the metabolic features of hepatocellular …
metastasis. In this report, we characterized the metabolic features of hepatocellular …
Chemometrics in metabonomics
We provide an overview of how the underlying philosophy of chemometrics is integrated
throughout metabonomic studies. Four steps are demonstrated:(1) definition of the aim,(2) …
throughout metabonomic studies. Four steps are demonstrated:(1) definition of the aim,(2) …
Multi‐dimensional mass spectrometry‐based shotgun lipidomics and novel strategies for lipidomic analyses
X Han, K Yang, RW Gross - Mass spectrometry reviews, 2012 - Wiley Online Library
Since our last comprehensive review on multi‐dimensional mass spectrometry‐based
shotgun lipidomics (Mass Spectrom. Rev. 24 (2005), 367), many new developments in the …
shotgun lipidomics (Mass Spectrom. Rev. 24 (2005), 367), many new developments in the …
[HTML][HTML] Metabolomics for the masses: The future of metabolomics in a personalized world
Current clinical practices focus on a small number of biochemical directly related to the
pathophysiology with patients and thus only describe a very limited metabolome of a patient …
pathophysiology with patients and thus only describe a very limited metabolome of a patient …
Applications of liquid chromatography coupled to mass spectrometry-based metabolomics in clinical chemistry and toxicology: A review
The metabolome is the set of small molecular mass organic compounds found in a given
biological media. It includes all organic substances naturally occurring from the metabolism …
biological media. It includes all organic substances naturally occurring from the metabolism …
NMR-based metabolic profiling and metabonomic approaches to problems in molecular toxicology
We have reviewed the main contributions to the development of NMR-based metabonomic
and metabolic profiling approaches for toxicological assessment, biomarker discovery, and …
and metabolic profiling approaches for toxicological assessment, biomarker discovery, and …
Current trends and future requirements for the mass spectrometric investigation of microbial, mammalian and plant metabolomes
WB Dunn - Physical biology, 2008 - iopscience.iop.org
The functional levels of biological cells or organisms can be separated into the genome,
transcriptome, proteome and metabolome. Of these the metabolome offers specific …
transcriptome, proteome and metabolome. Of these the metabolome offers specific …