A novel review of homocysteine and pregnancy complications

C Dai, Y Fei, J Li, Y Shi, X Yang - BioMed research international, 2021 - Wiley Online Library
Homocysteine (Hct) is a substance produced in the metabolism of methionine. It is an
essential type of amino acid gained from the daily diet. Methylenetetrahydrofolate reductase …

Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 …

O Asbaghi, D Ashtary-Larky, R Bagheri… - Critical Reviews in …, 2022 - Taylor & Francis
Folic acid supplementation has received considerable attention in the literature, yet there is
a large discrepancy in its effects on lipid markers in adults. Therefore, this systematic review …

[PDF][PDF] Folate deficiency and gene polymorphisms of MTHFR, MTR and MTRR elevate the hyperhomocysteinemia risk

WX Li, F Cheng, AJ Zhang, SX Dai, GH Li, WW Lv… - Clin Lab, 2017 - researchgate.net
We aimed to investigate the joint effect of homocysteine metabolism gene polymorphisms,
as well as the folate deficiency on the risk of HHcy in a Chinese hypertensive population …

[HTML][HTML] Arsenic, one carbon metabolism and diabetes-related outcomes in the Strong Heart Family Study

MJ Spratlen, M Grau-Perez, JG Umans… - Environment …, 2018 - Elsevier
Background Inorganic arsenic exposure and inter-individual differences in its metabolism
have been associated with cardiometabolic risk. A more efficient arsenic metabolism profile …

[HTML][HTML] Association between ACE (rs4646994), FABP2 (rs1799883), MTHFR (rs1801133), FTO (rs9939609) genes polymorphism and type 2 diabetes with …

ST Raza, S Abbas, Z Siddiqi… - International journal of …, 2017 - ncbi.nlm.nih.gov
Diabetic dyslipidemia is one of the leading causes of coronary artery disease (CAD) death.
Genetic and environmental factors play an important role in the development of type 2 …

Interactions of homocysteine and conventional predisposing factors on hypertension in Chinese adults

B Yang, S Fan, X Zhi, J He, P Ma, L Yu… - The Journal of …, 2017 - Wiley Online Library
This study aimed to investigate whether conventional predisposing factors modify the
associations of homocysteine with blood pressure levels and hypertension. A total of 2615 …

Methylenetetrahydrofolate reductase deficiency and high-dose FA supplementation disrupt embryonic development of energy balance and metabolic homeostasis in …

R Simonian, E Pannia, R Hammoud… - Human Molecular …, 2023 - academic.oup.com
Folic acid (synthetic folate, FA) is consumed in excess in North America and may interact
with common pathogenic variants in methylenetetrahydrofolate reductase (MTHFR); the …

Interactions between genetic variants involved in the folate metabolic pathway and serum lipid, homocysteine levels on the risk of recurrent spontaneous abortion

Z Lin, Q Li, Y Sun, J Huang, W Wang, J Fu, J Xu… - Lipids in health and …, 2019 - Springer
Background The interaction between folate pathway gene polymorphisms and
homocysteine, serum lipid leverls are poorly understood in patients with recurrent …

Associations of homocysteine status and homocysteine metabolism enzyme polymorphisms with hypertension and dyslipidemia in a Chinese hypertensive population

X Yuan, T Wang, J Gao, Y Wang, Y Chen… - Clinical and …, 2020 - Taylor & Francis
ABSTRACT Background: Hypertension (HTN), dyslipidemia and hyperhomocysteinemia
(HHcy) are risk factors for cardiovascular disease (CVD). Methods: Hypertensive Chinese …

Functional roles of folic acid in alleviating dexamethasone‐induced fatty liver syndrome in laying hens

X Sun, J Ma, C Wang, Z Ren, X Yang… - Animal Research and …, 2024 - Wiley Online Library
Fatty liver syndrome (FLS) poses a threat to the poultry industry due to its high occurrence
and mortality rate. Folic acid (FA) is a coenzyme crucial for one‐carbon metabolism …