Diabetic neuropathy is a common complication of both type 1 and type 2 diabetes, which
affects over 90% of the diabetic patients. Although pain is one of the main symptoms of …

Capsaicin, the major active constituent of chilli, is an agonist on transient receptor potential
vanilloid channel 1 (TRPV1). TRPV1 is present on many metabolically active tissues …

The use of food supplements for weight loss purposes has rapidly gained popularity as the
prevalence of obesity increases. Navigating through the vast, often low quality, literature …

Background Pain localization is one of the hallmarks for the choice of first-line treatment in
neuropathic pain. This literature review has been conducted to provide an overview of the …

Background. Endothelial dysfunction and cardiomyopathy are considered to be important
vascular complications associated with diabetes. This study was designed to investigate …

Neuropathic pain is caused by a lesion or disease affecting the somatosensory system and
is difficult to manage, often proving refractory to existing treatments. In more than half of …

Animal models of pain consist of modeling a pain-like state and measuring the consequent
behavior. The first animal models of neuropathic pain (NP) were developed in rodents with a …

Osteoarthritis prevalence is expected to increase markedly in the Asia-Pacific region due to
rapid population aging. Identifying effective and safe therapeutic options to manage …

Neuropathic pain is a complex and debilitating condition that affects millions of people
worldwide. While several treatment options are available, they often have limited efficacy …

Flavonoids are secondary metabolites that are widely distributed in plants. These phenolic
compounds are classified into various subgroups based on their structures: flavones …