Background Liposomal bupivacaine is purported to extend analgesia of peripheral nerve
blocks when administered perineurally. However, evidence of the clinical effectiveness of …

The authors provide a comprehensive summary of all randomized, controlled trials (n= 76)
involving the clinical administration of liposomal bupivacaine (Exparel; Pacira …

Nanomedicines have historically struggled to find clinical relevance and to achieve
translation successfully. In this Perspective, we discuss possible reasons for this difficulty …

Background Liposomal bupivacaine is reported to prolong the duration of analgesia when
used for abdominal fascial plane blocks compared to plain local anesthetics; however …

Background/Importance Liposomal bupivacaine (LB) is a prolonged release formulation of
conventional bupivacaine designed for prolonging local or peripheral regional single …

Regional analgesia has been increasing in popularity due to its opioid-sparing analgesic
effects and utility in multimodal analgesia strategies. Several regional techniques have been …

Postoperative pain management in plastic surgery has become a topic of increasing interest.
Pain is the perceived sensory and emotional reaction to actual or perceived tissue injury. 1 …

Background The opioid crisis has prompted surgeons to search for alternative postoperative
methods of analgesia. Liposomal bupivacaine is a long-acting local anesthetic formulation …

Background Deep inferior epigastric artery perforator (DIEP) flap is a common method of
breast reconstruction. Enhanced recovery after surgery (ERAS) postoperative protocols …

BACKGROUND: Pain is one of the most common adverse events after surgery. Regional
anesthesia techniques are effective for pain control but have limited duration of action …