We review the central tenets and neuroanatomical basis of the global neuronal workspace
(GNW) hypothesis, which attempts to account for the main scientific observations regarding …

Highlights•Adult human synapses show long-term potentiation and depression.•Activity-
dependent rules for associative plasticity have broad temporal windows.•Synaptic plasticity …

We describe an integrative model that encodes associations between related concepts in
the human hippocampal formation, constituting the skeleton of episodic memories. The …

Perception can be described as a process of inference, integrating bottom-up sensory inputs
and top-down expectations. However, it is unclear how this process is neurally implemented …

Perception can be cast as a process of inference, in which bottom-up signals are combined
with top-down predictions in sensory systems. In line with this, neural activity in sensory …

An indispensable feature of episodic memory is our ability to temporally piece together
different elements of an experience into a coherent memory. Hippocampal time cells …

Pattern separation is a basic principle of neuronal coding that precludes memory
interference in the hippocampus. Its existence is supported by numerous theoretical …

Deciphering the mechanisms of human memory is a central goal of neuroscience, both from
the point of view of the fundamental biology of memory and for its translational relevance …

Based on neuroimaging data, the insula is considered important for people to empathize
with the pain of others. Here, we present intracranial electroencephalographic (iEEG) …

Abstract Concept neurons in the medial temporal lobe respond to semantic features of
presented stimuli. Analyzing 61 concept neurons recorded from twelve patients who …