Metabotropic glutamatergic receptors and their ligands in drug addiction

L Pomierny-Chamioło, K Rup, B Pomierny… - Pharmacology & …, 2014 - Elsevier
Glutamatergic excitatory transmission is implicated in physiological and pathological
conditions like learning, memory, neuronal plasticity and emotions, while glutamatergic …

Retinal organization in the retinal degeneration 10 (rd10) mutant mouse: a morphological and ERG study

C Gargini, E Terzibasi, F Mazzoni… - Journal of Comparative …, 2007 - Wiley Online Library
ABSTRACT Retinal degeneration 10 (rd10) mice are a model of autosomal recessive
retinitis pigmentosa (RP), identified by Chang et al. in 2002 (Vision Res. 42: 517–525) …

OFF ganglion cells cannot drive the optokinetic reflex in zebrafish

F Emran, J Rihel, AR Adolph… - Proceedings of the …, 2007 - National Acad Sciences
Whereas the zebrafish retina has long been an important model system for developmental
and genetic studies, little is known about the responses of the inner retinal neurons. Here we …

TRPM1 forms complexes with nyctalopin in vivo and accumulates in postsynaptic compartment of ON-bipolar neurons in mGluR6-dependent manner

Y Cao, E Posokhova… - Journal of Neuroscience, 2011 - Soc Neuroscience
Synaptic transmission between light-sensory photoreceptor cells and downstream ON-
bipolar neurons plays an important role for vertebrate vision. This process is mediated by the …

LRIT 3 is essential to localize TRPM 1 to the dendritic tips of depolarizing bipolar cells and may play a role in cone synapse formation

M Neuillé, CW Morgans, Y Cao, E Orhan… - European Journal of …, 2015 - Wiley Online Library
Mutations in LRIT 3 lead to complete congenital stationary night blindness (cCSNB). The
exact role of LRIT 3 in ON‐bipolar cell signaling cascade remains to be elucidated …

Retina-specific GTPase accelerator RGS11/Gβ5S/R9AP is a constitutive heterotrimer selectively targeted to mGluR6 in ON-bipolar neurons

Y Cao, I Masuho, H Okawa, K Xie, J Asami… - Journal of …, 2009 - Soc Neuroscience
Members of the R7 family of the regulators of G-protein signaling (R7 RGS) proteins form
multi-subunit complexes that play crucial roles in processing the light responses of retinal …

[HTML][HTML] Retinal parallel pathways: seeing with our inner fish

C Joselevitch, M Kamermans - Vision research, 2009 - Elsevier
The general organization of the vertebrate retina is highly conserved, in spite of structural
variations that occur in different animal classes. The retinas of cyprinid fish, for example …

Orphan receptor GPR179 forms macromolecular complexes with components of metabotropic signaling cascade in retina ON-bipolar neurons

C Orlandi, Y Cao… - … ophthalmology & visual …, 2013 - iovs.arvojournals.org
Purpose.: In the mammalian retina, synaptic transmission between light-excited rod
photoreceptors and downstream ON-bipolar neurons is indispensable for dim vision, and …

[HTML][HTML] PKCα is essential for the proper activation and termination of rod bipolar cell response

K Ruether, A Feigenspan, J Pirngruber… - … & visual science, 2010 - jov.arvojournals.org
Purpose.: Protein kinase (PKC)-α is abundant in retinal bipolar cells. This study was
performed to explore its role in visual processing. Methods.: PKCα-knockout (Prkca−/−) mice …

Probing neurochemical structure and function of retinal ON bipolar cells with a transgenic mouse

A Dhingra, P Sulaiman, Y Xu, ME Fina… - Journal of …, 2008 - Wiley Online Library
Retinal ON bipolar cells make up about 70% of all bipolar cells. Glutamate hyperpolarizes
these cells by binding to the metabotropic glutamate receptor mGluR6, activating the G …