[HTML][HTML] Alzheimer's disease treatment: the search for a breakthrough
AB Reiss, D Muhieddine, B Jacob, M Mesbah… - Medicina, 2023 - mdpi.com
As the search for modalities to cure Alzheimer's disease (AD) has made slow progress,
research has now turned to innovative pathways involving neural and peripheral …
research has now turned to innovative pathways involving neural and peripheral …
Melatonin as an antiepileptic molecule: therapeutic implications via neuroprotective and inflammatory mechanisms
E Akyuz, I Kullu, A Arulsamy… - ACS chemical …, 2021 - ACS Publications
Epilepsy is a result of unprovoked, uncontrollable, and repetitive outburst of abnormal and
excessive electrical discharges, known as seizures, in the neurons. Epilepsy is a …
excessive electrical discharges, known as seizures, in the neurons. Epilepsy is a …
TRPV1 and TRPA1 in Lung Inflammation and Airway Hyperresponsiveness Induced by Fine Particulate Matter (PM2.5)
M Xu, Y Zhang, M Wang, H Zhang… - Oxidative medicine …, 2019 - Wiley Online Library
Exposure to fine particulate matter (PM2. 5) has been associated with lung inflammation and
airway hyperresponsiveness (AHR). Transient receptor potential (TRP) vanilloid 1 (TRPV1) …
airway hyperresponsiveness (AHR). Transient receptor potential (TRP) vanilloid 1 (TRPV1) …
Flavonoids isolated from loquat (Eriobotrya japonica) leaves inhibit oxidative stress and inflammation induced by cigarette smoke in COPD mice: the role of TRPV1 …
T Jian, J Chen, X Ding, H Lv, J Li, Y Wu, B Ren… - Food & function, 2020 - pubs.rsc.org
Chronic obstructive pulmonary disease (COPD) is a chronic, progressive lung disease with
few successful treatments, and is strongly associated with cigarette smoking (CS). Since the …
few successful treatments, and is strongly associated with cigarette smoking (CS). Since the …
[HTML][HTML] Luteolin alleviates oxidative stress in chronic obstructive pulmonary disease induced by cigarette smoke via modulation of the TRPV1 and CYP2A13/NRF2 …
L Zhou, T Jian, Y Wan, R Huang, H Fang… - International Journal of …, 2023 - mdpi.com
The current study aims to investigate the therapeutic potential of luteolin (Lut), a naturally
occurring flavonoid found in various medicinal plants, for treating chronic obstructive …
occurring flavonoid found in various medicinal plants, for treating chronic obstructive …
[HTML][HTML] Role of TRPA1/TRPV1 in acute ozone exposure induced murine model of airway inflammation and bronchial hyperresponsiveness
C Li, H Zhang, L Wei, Q Liu, M Xie, J Weng… - Journal of Thoracic …, 2022 - ncbi.nlm.nih.gov
Background Transient receptor potential (TRP) ankyrin 1 (TRPA1) and vanilloid 1 (TRPV1)
mediate the development of lung injury and inflammation. This study investigated the role …
mediate the development of lung injury and inflammation. This study investigated the role …
Involvement of TRPM7 channel on the induction of diabetic neuropathic pain in mice: protective role of selenium and curcumin
B Aydın, M Nazıroğlu - Biological Trace Element Research, 2023 - Springer
Excessive levels of the mitochondrial reactive oxygen radical (mitSOX) and Ca2+ influx were
found to cause neuropathic pain in patients with diabetes mellitus (DM). Naltriben (NLT) and …
found to cause neuropathic pain in patients with diabetes mellitus (DM). Naltriben (NLT) and …
[HTML][HTML] Feed restriction alleviates chronic thermal stress-induced liver oxidation and damages via reducing lipid accumulation in channel catfish (Ictalurus punctatus)
Q Lu, Y Gong, L Xi, Y Liu, W Xu, H Liu, J Jin, Z Zhang… - Antioxidants, 2022 - mdpi.com
Caloric restriction is known to suppress oxidative stress in organ systems. However, whether
caloric/feed restriction alleviates chronic thermal stress in aquatic animals remains …
caloric/feed restriction alleviates chronic thermal stress in aquatic animals remains …
Amyloidosis increase is not attenuated by long-term calorie restriction or related to neuron density in the prefrontal cortex of extremely aged rhesus macaques
GA Stonebarger, HF Urbanski, RL Woltjer, KL Vaughan… - Geroscience, 2020 - Springer
As human lifespan increases and the population ages, diseases of aging such as
Alzheimer's disease (AD) are a major cause for concern. Although calorie restriction (CR) as …
Alzheimer's disease (AD) are a major cause for concern. Although calorie restriction (CR) as …
Mitochondrial Redox State, Bioenergetics, and Calcium Transport in Caloric Restriction: a Metabolic Nexus
EA Vilas-Boas, AJ Kowaltowski - Free Radical Biology and Medicine, 2024 - Elsevier
Mitochondria congregate central reactions in energy metabolism, many of which involve
electron transfer. As such, they are expected to both respond to changes in nutrient supply …
electron transfer. As such, they are expected to both respond to changes in nutrient supply …