Molecular regulations of circadian rhythm and implications for physiology and diseases
The term “circadian rhythms” describes endogenous oscillations with ca. 24-h period
associated with the earth's daily rotation and light/dark cycle. Such rhythms reflect the …
associated with the earth's daily rotation and light/dark cycle. Such rhythms reflect the …
The functional and clinical significance of the 24-hour rhythm of circulating glucocorticoids
Adrenal glucocorticoids are major modulators of multiple functions, including energy
metabolism, stress responses, immunity, and cognition. The endogenous secretion of …
metabolism, stress responses, immunity, and cognition. The endogenous secretion of …
New insights into the circadian rhythm and its related diseases
Y Xie, Q Tang, G Chen, M Xie, S Yu, J Zhao… - Frontiers in …, 2019 - frontiersin.org
Circadian rhythms (CR) are a series of endogenous autonomous oscillators generated by
the molecular circadian clock which acting on coordinating internal time with the external …
the molecular circadian clock which acting on coordinating internal time with the external …
Circadian rhythms, time-restricted feeding, and healthy aging
ENC Manoogian, S Panda - Ageing research reviews, 2017 - Elsevier
Circadian rhythms optimize physiology and health by temporally coordinating cellular
function, tissue function, and behavior. These endogenous rhythms dampen with age and …
function, tissue function, and behavior. These endogenous rhythms dampen with age and …
Stress & sleep: A relationship lasting a lifetime
VL Martire, D Caruso, L Palagini, G Zoccoli… - Neuroscience & …, 2020 - Elsevier
Stress is an adaptative response aimed at restoring body homeostasis. The classical
neuroendocrine stress response involving the activation of the hypothalamic-pituitary …
neuroendocrine stress response involving the activation of the hypothalamic-pituitary …
[HTML][HTML] Stress: endocrine physiology and pathophysiology
C Tsigos, I Kyrou, E Kassi, GP Chrousos - Endotext [Internet], 2020 - ncbi.nlm.nih.gov
Stress constitutes a state of threatened homeostasis triggered by intrinsic or extrinsic
adverse forces (stressors) and is counteracted by an intricate repertoire of physiologic and …
adverse forces (stressors) and is counteracted by an intricate repertoire of physiologic and …
Central and peripheral circadian clocks in mammals
JA Mohawk, CB Green… - Annual review of …, 2012 - annualreviews.org
The circadian system of mammals is composed of a hierarchy of oscillators that function at
the cellular, tissue, and systems levels. A common molecular mechanism underlies the cell …
the cellular, tissue, and systems levels. A common molecular mechanism underlies the cell …
The mammalian circadian clock and its entrainment by stress and exercise
The mammalian circadian clock regulates day–night fluctuations in various physiological
processes. The circadian clock consists of the central clock in the suprachiasmatic nucleus …
processes. The circadian clock consists of the central clock in the suprachiasmatic nucleus …
Alcoholism: a systems approach from molecular physiology to addictive behavior
R Spanagel - Physiological reviews, 2009 - journals.physiology.org
Alcohol consumption is an integral part of daily life in many societies. The benefits
associated with the production, sale, and use of alcoholic beverages come at an enormous …
associated with the production, sale, and use of alcoholic beverages come at an enormous …
Circadian rhythms in the hypothalamo–pituitary–adrenal (HPA) axis
A Kalsbeek, R Van der Spek, J Lei, E Endert… - Molecular and cellular …, 2012 - Elsevier
The pronounced daily variation in the release of adrenal hormones has been at the heart of
the deciphering and understanding of the circadian timing system. Indeed, the first …
the deciphering and understanding of the circadian timing system. Indeed, the first …