Inside the diabetic brain: role of different players involved in cognitive decline
Diabetes mellitus is the most common metabolic disease, and its prevalence is increasing. A
growing body of evidence, both in animal models and epidemiological studies, has …
growing body of evidence, both in animal models and epidemiological studies, has …
Association between diabetes, diabetic retinopathy, and glaucoma
Y Li, W Mitchell, T Elze, N Zebardast - Current Diabetes Reports, 2021 - Springer
Abstract Purpose of Review The strength of the relationship between diabetes, diabetic
retinopathy (DR), and glaucoma remains controversial. We review evidence supporting and …
retinopathy (DR), and glaucoma remains controversial. We review evidence supporting and …
[HTML][HTML] Alzheimer's disease and type 2 diabetes-related alterations in brain mitochondria, autophagy and synaptic markers
C Carvalho, MS Santos, CR Oliveira… - Biochimica et Biophysica …, 2015 - Elsevier
We aimed to investigate mitochondrial function, biogenesis and autophagy in the brain of
type 2 diabetes (T2D) and Alzheimer's disease (AD) mice. Isolated brain mitochondria and …
type 2 diabetes (T2D) and Alzheimer's disease (AD) mice. Isolated brain mitochondria and …
[HTML][HTML] Integrative biology of extracellular vesicles in diabetes mellitus and diabetic complications
J Liu, Y Zhang, Y Tian, W Huang, N Tong, X Fu - Theranostics, 2022 - ncbi.nlm.nih.gov
Diabetes mellitus (DM) is a chronic systemic disease with increasing prevalence globally.
An important aspect of diabetic pathogenesis is cellular crosstalk and information exchange …
An important aspect of diabetic pathogenesis is cellular crosstalk and information exchange …
[HTML][HTML] Neurodegeneration in diabetic retinopathy: potential for novel therapies
AJ Barber, B Baccouche - Vision research, 2017 - Elsevier
The complex pathology of diabetic retinopathy (DR) affects both vascular and neural tissue.
The characteristics of neurodegeneration are well-described in animal models but have …
The characteristics of neurodegeneration are well-described in animal models but have …
Neurovascular unit: a new target for treating early stages of diabetic retinopathy
R Simó, O Simó-Servat, P Bogdanov, C Hernández - Pharmaceutics, 2021 - mdpi.com
The concept of diabetic retinopathy as a microvascular disease has evolved and is now
considered a more complex diabetic complication in which neurovascular unit impairment …
considered a more complex diabetic complication in which neurovascular unit impairment …
Caffeine consumption prevents diabetes-induced memory impairment and synaptotoxicity in the hippocampus of NONcZNO10/LTJ mice
Diabetic conditions are associated with modified brain function, namely with cognitive
deficits, through largely undetermined processes. More than understanding the underlying …
deficits, through largely undetermined processes. More than understanding the underlying …
Targeted pharmacotherapy against neurodegeneration and neuroinflammation in early diabetic retinopathy
KD Rolev, X Shu, Y Ying - Neuropharmacology, 2021 - Elsevier
Diabetic retinopathy (DR), the most frequent complication of diabetes, is one of the leading
causes of irreversible blindness in working-age adults and has traditionally been regarded …
causes of irreversible blindness in working-age adults and has traditionally been regarded …
GSK3β-mediated tau hyperphosphorylation triggers diabetic retinal neurodegeneration by disrupting synaptic and mitochondrial functions
Background Although diabetic retinopathy (DR) has long been considered as a
microvascular disorder, mounting evidence suggests that diabetic retinal …
microvascular disorder, mounting evidence suggests that diabetic retinal …
The pathogenesis and therapeutic approaches of diabetic neuropathy in the retina
T Oshitari - International journal of molecular sciences, 2021 - mdpi.com
Diabetic retinopathy is a major retinal disease and a leading cause of blindness in the world.
Diabetic retinopathy is a neurovascular disease that is associated with disturbances of the …
Diabetic retinopathy is a neurovascular disease that is associated with disturbances of the …