Pathogenesis of chronic obstructive pulmonary disease: understanding the contributions of gene–environment interactions across the lifespan

A Agustí, E Melen, DL DeMeo… - The Lancet …, 2022 - thelancet.com
The traditional view of chronic obstructive pulmonary disease (COPD) as a self-inflicted
disease caused by tobacco smoking in genetically susceptible individuals has been …

Update on the pathogenesis of chronic obstructive pulmonary disease

A Agustí, JC Hogg - New England Journal of Medicine, 2019 - Mass Medical Soc
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Chronic obstructive pulmonary disease exacerbation fundamentals: Diagnosis, treatment, prevention and disease impact

M MacLeod, A Papi, M Contoli, B Beghé, BR Celli… - …, 2021 - Wiley Online Library
In chronic obstructive pulmonary disease (COPD), exacerbations (ECOPD), characterized
by an acute deterioration in respiratory symptoms, are fundamental events impacting …

Comparison of World Health Organization and Asia-Pacific body mass index classifications in COPD patients

JU Lim, JH Lee, JS Kim, YI Hwang, TH Kim… - … journal of chronic …, 2017 - Taylor & Francis
Introduction A low body mass index (BMI) is associated with increased mortality and low
health-related quality of life in patients with COPD. The Asia-Pacific classification of BMI has …

[HTML][HTML] Indacaterol–glycopyrronium versus salmeterol–fluticasone for COPD

JA Wedzicha, D Banerji, KR Chapman… - … England Journal of …, 2016 - Mass Medical Soc
Background Most guidelines recommend either a long-acting beta-agonist (LABA) plus an
inhaled glucocorticoid or a long-acting muscarinic antagonist (LAMA) as the first-choice …

[HTML][HTML] Lung-function trajectories leading to chronic obstructive pulmonary disease

P Lange, B Celli, A Agustí, G Boje Jensen… - … England Journal of …, 2015 - Mass Medical Soc
Background Chronic obstructive pulmonary disease (COPD) is thought to result from an
accelerated decline in forced expiratory volume in 1 second (FEV1) over time. Yet it is …

Early-life origins of chronic obstructive pulmonary disease

FD Martinez - New England Journal of Medicine, 2016 - Mass Medical Soc
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Lung function trajectories in health and disease

A Agusti, R Faner - The Lancet Respiratory Medicine, 2019 - thelancet.com
The normal lung function trajectory from birth to death has three phases: a growth phase
(from birth to early adulthood), a plateau phase (that lasts for a few years), and a decline …

The asthma–COPD overlap syndrome

DS Postma, KF Rabe - New England Journal of Medicine, 2015 - Mass Medical Soc
The Asthma–COPD Overlap Syndrome | NEJM Skip to main content NEJM Group Follow Us
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[HTML][HTML] Role of diet in chronic obstructive pulmonary disease prevention and treatment

E Scoditti, M Massaro, S Garbarino, DM Toraldo - Nutrients, 2019 - mdpi.com
Chronic obstructive pulmonary disease is one of the leading causes of morbidity and
mortality worldwide and a growing healthcare problem. Identification of modifiable risk …