A comprehensive review on tyrosinase inhibitors
S Zolghadri, A Bahrami, MT Hassan Khan… - Journal of enzyme …, 2019 - Taylor & Francis
Tyrosinase is a multi-copper enzyme which is widely distributed in different organisms and
plays an important role in the melanogenesis and enzymatic browning. Therefore, its …
plays an important role in the melanogenesis and enzymatic browning. Therefore, its …
Tyrosinase inhibitors naturally present in plants and synthetic modifications of these natural products as anti-melanogenic agents: a review
Tyrosinase is a key enzyme target to design new chemical ligands against melanogenesis.
In the current review, different chemical derivatives are explored which have been used as …
In the current review, different chemical derivatives are explored which have been used as …
In silico identification of potential inhibitors of key SARS-CoV-2 3CL hydrolase (Mpro) via molecular docking, MMGBSA predictive binding energy calculations, and …
The incidence of 2019 novel corona virus (SARS-CoV-2) has created a medical emergency
throughout the world. Various efforts have been made to develop the vaccine or effective …
throughout the world. Various efforts have been made to develop the vaccine or effective …
Design, synthesis and ADMET prediction of bis-benzimidazole as anticancer agent
M Rashid - Bioorganic chemistry, 2020 - Elsevier
A new series of bis-benzimidazole clubbed with primary amine (3i-iii) and aromatic
aldehydes (4i-ix) were design and synthesize with an intention to search an anticancer lead …
aldehydes (4i-ix) were design and synthesize with an intention to search an anticancer lead …
Evaluation of oxindole derivatives as a potential anticancer agent against breast carcinoma cells: In vitro, in silico, and molecular docking study
In this study we have performed the in vitro anticancer activity of spiro oxindole derivatives
against MCF-7 (human Adreno carcinoma) and MDA-MB-231 (triple negative breast cancer) …
against MCF-7 (human Adreno carcinoma) and MDA-MB-231 (triple negative breast cancer) …
A practical strategy for exploring the pharmacological mechanism of luteolin against COVID-19/asthma comorbidity: findings of system pharmacology and …
YZ Xie, CW Peng, ZQ Su, HT Huang, XH Liu… - Frontiers in …, 2022 - frontiersin.org
Asthma patients may increase their susceptibility to SARS-CoV-2 infection and the poor
prognosis of coronavirus disease 2019 (COVID-19). However, anti-COVID-19/asthma …
prognosis of coronavirus disease 2019 (COVID-19). However, anti-COVID-19/asthma …
Structure-Based Virtual Screening of Furan-1,3,4-Oxadiazole Tethered N-phenylacetamide Derivatives as Novel Class of hTYR and hTYRP1 Inhibitors
Human tyrosinase (hTYR) is a key and rate-limiting enzyme along with human tyrosinase-
related protein-1 (hTYRP1), which are among the most prominent targets of inhibiting hyper …
related protein-1 (hTYRP1), which are among the most prominent targets of inhibiting hyper …
Novel 1, 2, 3-triazole compounds: Synthesis, In vitro xanthine oxidase inhibitory activity, and molecular docking studies
A Tan - Journal of Molecular Structure, 2020 - Elsevier
Abstract In this study, novel 1, 2, 3-triazole compounds containing carbasugar frameworks (5
and 6) were synthesized by the copper-catalyzed azide-alkyne cycloaddition reactions and …
and 6) were synthesized by the copper-catalyzed azide-alkyne cycloaddition reactions and …
Discovery of amphotericin B, an antifungal drug as tyrosinase inhibitor with potent anti-melanogenic activity
P Mahalapbutr, S Sabuakham, S Nasoontorn… - International Journal of …, 2023 - Elsevier
Tyrosinase, a rate-limiting enzyme for melanin production, has been the most efficient target
for the development of depigmenting agents. Although hydroquinone, kojic acid, and arbutin …
for the development of depigmenting agents. Although hydroquinone, kojic acid, and arbutin …
Molecular docking and dynamic simulation of AZD3293 and solanezumab effects against BACE1 to treat Alzheimer's disease
The design of novel inhibitors to target BACE1 with reduced cytotoxicity effects is a
promising approach to treat Alzheimer's disease (AD). Multiple clinical drugs and antibodies …
promising approach to treat Alzheimer's disease (AD). Multiple clinical drugs and antibodies …