Understanding lipotoxicity in NAFLD pathogenesis: is CD36 a key driver?
P Rada, Á González-Rodríguez, C García-Monzón… - Cell death & …, 2020 - nature.com
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease
worldwide. NAFLD stages range from simple steatosis (NAFL) to non-alcoholic …
worldwide. NAFLD stages range from simple steatosis (NAFL) to non-alcoholic …
Mechanisms of diabetic cardiomyopathy and potential therapeutic strategies: preclinical and clinical evidence
Y Tan, Z Zhang, C Zheng, KA Wintergerst… - Nature Reviews …, 2020 - nature.com
The pathogenesis and clinical features of diabetic cardiomyopathy have been well-studied
in the past decade, but effective approaches to prevent and treat this disease are limited …
in the past decade, but effective approaches to prevent and treat this disease are limited …
[HTML][HTML] CD36 tango in cancer: signaling pathways and functions
J Wang, Y Li - Theranostics, 2019 - ncbi.nlm.nih.gov
CD36, a scavenger receptor expressed in multiple cell types, mediates lipid uptake,
immunological recognition, inflammation, molecular adhesion, and apoptosis. CD36 is a …
immunological recognition, inflammation, molecular adhesion, and apoptosis. CD36 is a …
CD36 as a gatekeeper of myocardial lipid metabolism and therapeutic target for metabolic disease
JFC Glatz, LC Heather… - Physiological reviews, 2024 - journals.physiology.org
The multifunctional membrane glycoprotein CD36 is expressed in different types of cells and
plays a key regulatory role in cellular lipid metabolism, especially in cardiac muscle. CD36 …
plays a key regulatory role in cellular lipid metabolism, especially in cardiac muscle. CD36 …
Dynamic role of the transmembrane glycoprotein CD36 (SR-B2) in cellular fatty acid uptake and utilization
JFC Glatz, JJFP Luiken - Journal of lipid research, 2018 - ASBMB
The widely expressed transmembrane glycoprotein, cluster of differentiation 36 (CD36), a
scavenger receptor class B protein (SR-B2), serves many functions in lipid metabolism and …
scavenger receptor class B protein (SR-B2), serves many functions in lipid metabolism and …
Myocardial fatty acid metabolism in health and disease
There is a constant high demand for energy to sustain the continuous contractile activity of
the heart, which is met primarily by the β-oxidation of long-chain fatty acids. The control of …
the heart, which is met primarily by the β-oxidation of long-chain fatty acids. The control of …
The role of CD36 in cardiovascular disease
H Shu, Y Peng, W Hang, J Nie, N Zhou… - Cardiovascular …, 2022 - academic.oup.com
CD36, also known as the scavenger receptor B2, is a multifunctional receptor widely
expressed in various organs. CD36 plays a crucial role in the uptake of long-chain fatty …
expressed in various organs. CD36 plays a crucial role in the uptake of long-chain fatty …
Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity
E Fabbrini, F Magkos, BS Mohammed… - Proceedings of the …, 2009 - National Acad Sciences
Visceral adipose tissue (VAT) is an important risk factor for obesity-related metabolic
disorders. Therefore, a reduction in VAT has become a key goal in obesity management …
disorders. Therefore, a reduction in VAT has become a key goal in obesity management …
Membrane fatty acid transporters as regulators of lipid metabolism: implications for metabolic disease
JFC Glatz, JJFP Luiken, A Bonen - Physiological reviews, 2010 - journals.physiology.org
Long-chain fatty acids and lipids serve a wide variety of functions in mammalian
homeostasis, particularly in the formation and dynamic properties of biological membranes …
homeostasis, particularly in the formation and dynamic properties of biological membranes …
CD36 in chronic kidney disease: novel insights and therapeutic opportunities
CD36 (also known as scavenger receptor B2) is a multifunctional receptor that mediates the
binding and cellular uptake of long-chain fatty acids, oxidized lipids and phospholipids …
binding and cellular uptake of long-chain fatty acids, oxidized lipids and phospholipids …