The four natural DNA bases (A, T, G and C) associate in base pairs (A= T and G≡ C),
allowing the attached DNA strands to assemble into the canonical double helix of DNA (or …

DNA has been a key target for cancer therapy, with a range of compounds able to bind and
either impair its processing or induce damage. Targeting DNA with small molecules in a truly …

Ruthenium (II) polypyridyl complexes (RPCs) that emit from metal-to-ligand charge transfer
(MLCT) states have been developed as DNA probes and are being examined as potential …

Damaging DNA is a current and efficient strategy to fight against cancer cell proliferation.
Numerous mechanisms exist to counteract DNA damage, collectively referred to as the DNA …

Holliday 4-way junctions are key to important biological DNA processes (insertion,
recombination, and repair) and are dynamic structures that adopt either open or closed …

DNA three-way junction (TWJ) structures transiently form during key cellular processes such
as transcription, replication, and DNA repair. Despite their significance, the thermodynamics …

Translocation of DNA and RNA polymerases along their duplex substrates results in DNA
supercoiling. This torsional stress promotes the formation of plectonemic structures …

Photocatalytic water oxidation reaction by transition metal complexes remains a challenge
because of their poor stability under irradiation, especially for earth-abundant metal …

The human genome is replete with repetitive DNA sequences that can fold into
thermodynamically stable secondary structures such as hairpins and quadruplexes. Cellular …

DNA-based molecular electronics will require charges to be transported from one site within
a 2D or 3D architecture to another. While this has been shown previously in linear, π …