Calcium ion (Ca 2+) is a ubiquitous and versatile signaling molecule controlling a wide
variety of cellular processes, such as proliferation, cell death, migration, and immune …

Ca 2+ ions are key second messengers in both excitable and non-excitable cells. Owing to
the rather pleiotropic nature of Ca 2+ transporters and other Ca 2+-binding proteins …

Lung cancer with the highest mortality poses a great threat to human health. Ferroptosis
therapy has recently been raised as a promising strategy for lung cancer treatment by …

Herein, we prepared CaH 2 nanoparticles through liquid-phase exfoliation and first applied
them as an antitumor therapeutic agent. Being dispersed in low-molecular-weight …

Mitochondria are energy factories of cells and are important pivots for intracellular
interactions with other organelles. They interact with the endoplasmic reticulum …

The conversion of endogenous H2O2 into toxic hydroxyl radical (• OH) via catalytic
nanoparticles is explored for tumor therapy and received considerable success. The intrinsic …

The study of extracellular vesicles (EVs) is a rapidly evolving field, owing in large part to
recent advances in the realization of their significant contributions to normal physiology and …

The ubiquitous second messenger Ca2+ has long been recognized as a key regulator in
cell migration. Locally confined Ca2+, in particular, is essential for building front-to-rear …

Extracellular vesicles (EVs) are a heterogeneous group of membrane-limited vesicles and
multi-signal messengers loaded with biomolecules. Exosomes and ectosomes are two …

Inositol 1, 4, 5-trisphosphate receptors (IP3Rs) are one of the two types of tetrameric ion
channels that release calcium ion (Ca2+) from the endoplasmic reticulum (ER) into the …