Integrated sensor arrays for biological and chemical analysis
J Rothberg, J Bustillo, M Milgrew, J Schultz… - US Patent …, 2015 - Google Patents
The invention is directed to apparatus and chips comprising a large scale chemical field
effect transistor arrays that include an array of sample-retaining regions capable of retaining …
effect transistor arrays that include an array of sample-retaining regions capable of retaining …
Methods and apparatus for measuring analytes using large scale FET arrays
JM Rothberg, W Hinz, KL Johnson, J Bustillo - US Patent 9,269,708, 2016 - Google Patents
2012-01-23 Assigned to ION TORRENT INCORPORATED reassignment ION TORRENT
INCORPORATED ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
INCORPORATED ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
CCD-based multi-transistor active pixel sensor array
F Keith, M Milgrew - US Patent 8,772,698, 2014 - Google Patents
(52) Sc l. 2SO/214 R 250f2O8. 1422/82O3: obtain gain by accumulating charge into another
electrode or onto a floating diffusion (FD) node or directly onto the col umn line. It is …
electrode or onto a floating diffusion (FD) node or directly onto the col umn line. It is …
Array configuration and readout scheme
K Johnson, J Jordan, P Levine, M Milgrew - US Patent 8,731,847, 2014 - Google Patents
The described embodiments may provide a chemical detec tion circuit that may comprise a
plurality of first output cir cuits at a first side and a plurality of second output circuits at a …
plurality of first output cir cuits at a first side and a plurality of second output circuits at a …
Methods and apparatus for measuring analytes
T Rearick, M Davey, M Beauchemin - US Patent 8,776,573, 2014 - Google Patents
A method, computer program product, and system are provided to calibrate a sensor array
with a plurality of sensors. The method can include sweeping a voltage of a reference …
with a plurality of sensors. The method can include sweeping a voltage of a reference …
Active chemically-sensitive sensors
M Milgrew - US Patent 8,698,212, 2014 - Google Patents
Methods and apparatus relating to FET arrays for monitoring chemical and/or biological
reactions such as nucleic acid sequencing-by-synthesis reactions. Some methods provided …
reactions such as nucleic acid sequencing-by-synthesis reactions. Some methods provided …
Method and system for delta double sampling
F Keith, J Yang - US Patent 8,796,036, 2014 - Google Patents
An array of sensors arranged in matched pairs of transistors with an output formed on a first
transistor and a sensor formed on the second transistor of the matched pair. The matched …
transistor and a sensor formed on the second transistor of the matched pair. The matched …
Active chemically-sensitive sensors with correlated double sampling
M Milgrew - US Patent 8,742,469, 2014 - Google Patents
Methods and apparatus relating to FET arrays for monitoring chemical and/or biological
reactions such as nucleic acid sequencing-by-synthesis reactions. Some methods provided …
reactions such as nucleic acid sequencing-by-synthesis reactions. Some methods provided …
Active chemically-sensitive sensors with in-sensor current sources
M Milgrew - US Patent 8,766,327, 2014 - Google Patents
Methods and apparatus relating to FET arrays for monitoring chemical and/or biological
reactions such as nucleic acid sequencing-by-synthesis reactions. Some methods provided …
reactions such as nucleic acid sequencing-by-synthesis reactions. Some methods provided …
Methods and apparatus for high-speed operation of a chemically-sensitive sensor array
J Rothberg, W Hinz, K Johnson, J Bustillo - US Patent 8,685,230, 2014 - Google Patents
2012-10-23 Assigned to ION TORRENT SYSTEMS INCORPORATED reassignment ION
TORRENT SYSTEMS INCORPORATED ASSIGNMENT OF ASSIGNORS INTEREST (SEE …
TORRENT SYSTEMS INCORPORATED ASSIGNMENT OF ASSIGNORS INTEREST (SEE …