The advantages and challenges of using endolysins in a clinical setting
Antibiotic-resistant pathogens are increasingly more prevalent and problematic. Traditional
antibiotics are no longer a viable option for dealing with these multidrug-resistant microbes …
antibiotics are no longer a viable option for dealing with these multidrug-resistant microbes …
Bacteriophage-encoded virion-associated enzymes to overcome the carbohydrate barriers during the infection process
A Latka, B Maciejewska, G Majkowska-Skrobek… - Applied microbiology …, 2017 - Springer
Bacteriophages are bacterial viruses that infect the host after successful receptor recognition
and adsorption to the cell surface. The irreversible adherence followed by genome material …
and adsorption to the cell surface. The irreversible adherence followed by genome material …
[HTML][HTML] Alternatives to overcoming bacterial resistances: State-of-the-art
AC Rios, CG Moutinho, FC Pinto, FS Del Fiol… - Microbiological …, 2016 - Elsevier
Worldwide, bacterial resistance to chemical antibiotics has reached such a high level that
endangers public health. Presently, the adoption of alternative strategies that promote the …
endangers public health. Presently, the adoption of alternative strategies that promote the …
Viruses versus bacteria—novel approaches to phage therapy as a tool against multidrug-resistant pathogens
TM Viertel, K Ritter, HP Horz - Journal of Antimicrobial …, 2014 - academic.oup.com
Bacteriophage therapy (the application of phages to treat bacterial infections) has a tradition
dating back almost a century, but interest in phage therapy slowed down in the West when …
dating back almost a century, but interest in phage therapy slowed down in the West when …
Bacteriophage endolysins: applications for food safety
M Schmelcher, MJ Loessner - Current opinion in biotechnology, 2016 - Elsevier
Highlights•Endolysins are promising agents for detection and control of foodborne
pathogens.•Cell wall binding domains can be used for specific detection of bacteria in …
pathogens.•Cell wall binding domains can be used for specific detection of bacteria in …
Effective removal of staphylococcal biofilms by the endolysin LysH5
D Gutierrez, P Ruas-Madiedo, B Martinez… - PloS one, 2014 - journals.plos.org
Staphylococcal biofilms are a major concern in both clinical and food settings because they
are an important source of contamination. The efficacy of established cleaning procedures is …
are an important source of contamination. The efficacy of established cleaning procedures is …
The dawn of phage therapy
Bacteriophages or phages, being the most abundant entities on earth, represent a potential
solution to a diverse range of problems. Phages are successful antibacterial agents whose …
solution to a diverse range of problems. Phages are successful antibacterial agents whose …
Engineering of phage-derived lytic enzymes: improving their potential as antimicrobials
C São-José - Antibiotics, 2018 - mdpi.com
Lytic enzymes encoded by bacteriophages have been intensively explored as alternative
agents for combating bacterial pathogens in different contexts. The antibacterial character of …
agents for combating bacterial pathogens in different contexts. The antibacterial character of …
[HTML][HTML] Design strategies for positively charged endolysins: insights into Artilysin development
JV Carratalá, A Arís, E Garcia-Fruitós… - Biotechnology …, 2023 - Elsevier
Endolysins are bacteriophage-encoded enzymes that can specifically degrade the
peptidoglycan layer of bacterial cell wall, making them an attractive tool for the development …
peptidoglycan layer of bacterial cell wall, making them an attractive tool for the development …
Are Phage Lytic Proteins the Secret Weapon To Kill Staphylococcus aureus?
D Gutiérrez, L Fernández, A Rodríguez, P García - MBio, 2018 - Am Soc Microbiol
Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most threatening
microorganisms for global human health. The current strategies to reduce the impact of S …
microorganisms for global human health. The current strategies to reduce the impact of S …