Immunoregulatory receptors are essential for orchestrating an immune response as well as
appropriate inflammation in infectious and non-communicable diseases. Among them …

Human leukocyte immunoglobulin-like receptors (LILR) are a family of 11 functional genes
encoding five activating (LILRA1, 2, 4–6), five inhibitory (LILRB1–5) and one soluble …

Tumor-associated myeloid cells maintain immunosuppressive microenvironments within
tumors. Identification of myeloid-specific receptors to modulate tumor-associated …

The understanding of the foreign-body responses to implanted biomaterials would benefit
from the reconstruction of intracellular and intercellular signalling networks in the …

Co-inhibitory and checkpoint molecules suppress T cell function in the tumor
microenvironment, thereby rendering T cells dysfunctional. Although immune checkpoint …

Immunity that controls parasitemia and inflammation during Plasmodium falciparum (Pf)
malaria can be acquired with repeated infections. A limited understanding of this complex …

The immune system is tightly regulated by the activity of stimulatory and inhibitory immune
receptors. This immune homeostasis is usually disturbed during chronic viral infection …

Despite advances in identifying the key immunoregulatory roles of many of the human
leukocyte immunoglobulin-like receptor (LILR) family members, the function of the inhibitory …

Human leukocyte immunoglobulin (Ig)-like receptors (LILR) are a family of 11 innate
immunomodulatory receptors, primarily expressed on lymphoid and myeloid cells. LILRs are …

Neutrophils have a crucial role in defense against microbes. Immune receptors allow
neutrophils to sense their environment, with many receptors functioning to recognize signs …