Monoclonal antibodies (mAbs) are appealing as potential therapeutics and prophylactics for
viral infections owing to characteristics such as their high specificity and their ability to …

Proteins that self-assemble into polyhedral shell-like structures are useful molecular
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …

The development of a portfolio of COVID-19 vaccines to vaccinate the global population
remains an urgent public health imperative. Here we demonstrate the capacity of a subunit …

Since their initial development, cell membrane-coated nanoparticles (CNPs) have become
increasingly popular in the biomedical field. Despite their inherent versatility and ability to …

Inflammation-associated diseases encompass a range of infectious diseases and non-
infectious inflammatory diseases, which continuously pose one of the most serious threats to …

The need for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) next-
generation vaccines has been highlighted by the rise of variants of concern (VoCs) and the …

Recent breakthroughs in AI coupled with the rapid accumulation of protein sequence and
structure data have radically transformed computational protein design. New methods …

As the number of individuals vaccinated against SARS-CoV-2 rises worldwide, population-
level data regarding the vaccines' ability to reduce infection are being generated …

The emergence of SARS-CoV-2 variants and potentially other highly pathogenic
sarbecoviruses in the future highlights the need for pan-sarbecovirus vaccines. Here, we …

Vaccine administration by subcutaneous or intramuscular injection is the most commonly
prescribed route for inoculation, however, it is often associated with some deficiencies such …