Nucleases: diversity of structure, function and mechanism
W Yang - Quarterly reviews of biophysics, 2011 - cambridge.org
Nucleases cleave the phosphodiester bonds of nucleic acids and may be endo or exo,
DNase or RNase, topoisomerases, recombinases, ribozymes, or RNA splicing enzymes. In …
DNase or RNase, topoisomerases, recombinases, ribozymes, or RNA splicing enzymes. In …
The catalytic mechanisms of binuclear metallohydrolases
Binuclear metallohydrolases are a structurally diverse group of enzymes that use binuclear
metal ion centers to catalyze the hydrolysis of amides and esters of carboxylic and …
metal ion centers to catalyze the hydrolysis of amides and esters of carboxylic and …
Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF 2α‐mediated stress signaling
CXC Santos, AD Hafstad, M Beretta, M Zhang… - The EMBO …, 2016 - embopress.org
Phosphorylation of translation initiation factor 2α (eIF 2α) attenuates global protein synthesis
but enhances translation of activating transcription factor 4 (ATF 4) and is a crucial …
but enhances translation of activating transcription factor 4 (ATF 4) and is a crucial …
Structural basis for the catalytic activity of human serine/threonine protein phosphatase-5
MR Swingle, RE Honkanen, EM Ciszak - Journal of Biological Chemistry, 2004 - ASBMB
Serine/threonine protein phosphatase-5 (PP5) affects many signaling networks that regulate
cell growth and cellular responses to stress. Here we report the crystal structure of the PP5 …
cell growth and cellular responses to stress. Here we report the crystal structure of the PP5 …
Dual function of protein phosphatase 5 (PPP5C): An emerging therapeutic target for drug discovery
H Zhang, Q Zhang, J Tu, Q You, L Wang - European Journal of Medicinal …, 2023 - Elsevier
Phosphorylation of proteins is reversibly controlled by the kinases and phosphatases in
many posttranslational regulation patterns. Protein phosphatase 5 (PPP5C) is a …
many posttranslational regulation patterns. Protein phosphatase 5 (PPP5C) is a …
Quantitative analysis of dinuclear manganese (II) EPR spectra
AP Golombek, MP Hendrich - Journal of Magnetic Resonance, 2003 - Elsevier
A quantitative method for the analysis of EPR spectra from dinuclear Mn (II) complexes is
presented. The complex [(Me3TACN) 2Mn (II) 2 (μ-OAc) 3] BPh4 (1)(Me3TACN= N, N …
presented. The complex [(Me3TACN) 2Mn (II) 2 (μ-OAc) 3] BPh4 (1)(Me3TACN= N, N …
Curcumin opens cystic fibrosis transmembrane conductance regulator channels by a novel mechanism that requires neither ATP binding nor dimerization of the …
W Wang, K Bernard, G Li, KL Kirk - Journal of Biological Chemistry, 2007 - ASBMB
Cystic fibrosis transmembrane conductance regulator (CFTR) chloride channels are
essential mediators of salt transport across epithelia. Channel opening normally requires …
essential mediators of salt transport across epithelia. Channel opening normally requires …
The global transcriptional response of Bacillus subtilis to manganese involves the MntR, Fur, TnrA and σB regulons
E Guedon, CM Moore, Q Que, T Wang… - Molecular …, 2003 - Wiley Online Library
We have used DNA microarrays to monitor the global transcriptional response of Bacillus
subtilis to changes in manganese availability. Mn (II) leads to the MntR‐dependent …
subtilis to changes in manganese availability. Mn (II) leads to the MntR‐dependent …
The Rv0805 Gene from Mycobacterium tuberculosis Encodes a 3',5'-Cyclic Nucleotide Phosphodiesterase: Biochemical and Mutational Analysis
AR Shenoy, N Sreenath, M Podobnik, M Kovacevic… - Biochemistry, 2005 - ACS Publications
Mycobacterium tuberculosis is an important human pathogen and has developed
sophisticated mechanisms to evade the host immune system. These could involve the use of …
sophisticated mechanisms to evade the host immune system. These could involve the use of …
Engineered Bacillus subtilis harbouring gene of d-tagatose 3-epimerase for the bioconversion of d-fructose into d-psicose through fermentation
J Zhang, C Xu, X Chen, X Ruan, Y Zhang, H Xu… - Enzyme and Microbial …, 2020 - Elsevier
Abstract d-Psicose, as important rare sugar and epimer of d-fructose on the C-3 position,
displays unique health benefits and physiological functions in various fields. The production …
displays unique health benefits and physiological functions in various fields. The production …