Facing up to the global challenges of ageing
L Partridge, J Deelen, PE Slagboom - Nature, 2018 - nature.com
Longer human lives have led to a global burden of late-life disease. However, some older
people experience little ill health, a trait that should be extended to the general population …
people experience little ill health, a trait that should be extended to the general population …
Aging, lifestyle and dementia
Aging is the greatest risk factor for most diseases including cancer, cardiovascular disorders,
and neurodegenerative disease. There is emerging evidence that interventions that improve …
and neurodegenerative disease. There is emerging evidence that interventions that improve …
Neuroprotective mechanisms of astaxanthin: a potential therapeutic role in preserving cognitive function in age and neurodegeneration
B Grimmig, SH Kim, K Nash, PC Bickford… - Geroscience, 2017 - Springer
Astaxanthin (AXT) is a carotenoid with multiple health benefits. It is currently marketed as a
health supplement and is well known for its antioxidant capacity. Recent evidence has …
health supplement and is well known for its antioxidant capacity. Recent evidence has …
Intermittent fasting and cognitive performance–Targeting BDNF as potential strategy to optimise brain health
K Seidler, M Barrow - Frontiers in neuroendocrinology, 2022 - Elsevier
Aging is the major risk factor for neurodegenerative diseases, accelerated by excessive
calorie consumption and sedentary lifestyles. Bioenergetic challenges such as intermittent …
calorie consumption and sedentary lifestyles. Bioenergetic challenges such as intermittent …
Nutrients in the Prevention of Alzheimer's Disease
Alzheimer's disease (AD) is a disease caused by the complex interaction of multiple
mechanisms, some of which are still not fully understood. To date, pharmacological …
mechanisms, some of which are still not fully understood. To date, pharmacological …
[HTML][HTML] Comparing the effects of low-protein and high-carbohydrate diets and caloric restriction on brain aging in mice
Calorie restriction (CR) increases lifespan and improves brain health in mice. Ad libitum low-
protein, high-carbohydrate (LPHC) diets also extend lifespan, but it is not known whether …
protein, high-carbohydrate (LPHC) diets also extend lifespan, but it is not known whether …
Mechanisms of neuroplasticity and brain degeneration: strategies for protection during the aging process
M Toricelli, AAR Pereira, GS Abrao… - Neural regeneration …, 2021 - journals.lww.com
Aging is a dynamic and progressive process that begins at conception and continues until
death. This process leads to a decrease in homeostasis and morphological, biochemical …
death. This process leads to a decrease in homeostasis and morphological, biochemical …
One-year Mediterranean diet promotes epigenetic rejuvenation with country-and sex-specific effects: a pilot study from the NU-AGE project
Mediterranean diet has been proposed to promote healthy aging, but its effects on aging
biomarkers have been poorly investigated. We evaluated the impact of a 1-year …
biomarkers have been poorly investigated. We evaluated the impact of a 1-year …
The reverse transcriptase inhibitor 3TC protects against age‐related cognitive dysfunction
Aging is the primary risk factor for most neurodegenerative diseases, including Alzheimer's
disease. Major hallmarks of brain aging include neuroinflammation/immune activation and …
disease. Major hallmarks of brain aging include neuroinflammation/immune activation and …
Cognitive and behavioral evaluation of nutritional interventions in rodent models of brain aging and dementia
Evaluation of behavior and cognition in rodent models underpins mechanistic and
interventional studies of brain aging and neurodegenerative diseases, especially dementia …
interventional studies of brain aging and neurodegenerative diseases, especially dementia …