Mechanisms of metabolic reprogramming in cancer cells supporting enhanced growth and proliferation
C Schiliro, BL Firestein - Cells, 2021 - mdpi.com
Cancer cells alter metabolic processes to sustain their characteristic uncontrolled growth
and proliferation. These metabolic alterations include (1) a shift from oxidative …
and proliferation. These metabolic alterations include (1) a shift from oxidative …
[HTML][HTML] Mechanoresponsive metabolism in cancer cell migration and metastasis
Altered tissue mechanics and metabolism are defining characteristics of cancer that impact
not only proliferation but also migration. While migrating through a mechanically and …
not only proliferation but also migration. While migrating through a mechanically and …
Targeting glucose metabolism to suppress cancer progression: prospective of anti-glycolytic cancer therapy
AF Abdel-Wahab, W Mahmoud, RM Al-Harizy - Pharmacological research, 2019 - Elsevier
Most solid tumor cells adapt to their heterogeneous microenvironment by depending largely
on aerobic glycolysis for energy production, a phenomenon called the Warburg effect, which …
on aerobic glycolysis for energy production, a phenomenon called the Warburg effect, which …
Signal pathways and precision therapy of small-cell lung cancer
M Yuan, Y Zhao, HT Arkenau, T Lao, L Chu… - Signal transduction and …, 2022 - nature.com
Small-cell lung cancer (SCLC) encounters up 15% of all lung cancers, and is characterized
by a high rate of proliferation, a tendency for early metastasis and generally poor prognosis …
by a high rate of proliferation, a tendency for early metastasis and generally poor prognosis …
Targeting metabolism in cancer cells and the tumour microenvironment for cancer therapy
Targeting altered tumour metabolism is an emerging therapeutic strategy for cancer
treatment. The metabolic reprogramming that accompanies the development of malignancy …
treatment. The metabolic reprogramming that accompanies the development of malignancy …
Inhibition of glycolysis and glutaminolysis: an emerging drug discovery approach to combat cancer
Cancer cells have a very different metabolism from that of normal cells from which they are
derived. Their metabolism is elevated, which allows them to sustain higher proliferative rate …
derived. Their metabolism is elevated, which allows them to sustain higher proliferative rate …
Targeting glucose metabolism enzymes in cancer treatment: current and emerging strategies
Simple Summary Reprogramming of glucose metabolism is a hallmark of cancer and can be
targeted by therapeutic agents. Some metabolism regulators, such as ivosidenib and …
targeted by therapeutic agents. Some metabolism regulators, such as ivosidenib and …
Metabolic reprogramming in cancer: Mechanisms and therapeutics
S Nong, X Han, Y Xiang, Y Qian, Y Wei, T Zhang… - MedComm, 2023 - Wiley Online Library
Cancer cells characterized by uncontrolled growth and proliferation require altered
metabolic processes to maintain this characteristic. Metabolic reprogramming is a process …
metabolic processes to maintain this characteristic. Metabolic reprogramming is a process …
“An apple a day keeps the doctor away”: The potentials of apple bioactive constituents for chronic disease prevention
Apples are rich sources of selected micronutrients (eg, iron, zinc, vitamins C and E) and
polyphenols (eg, procyanidins, phloridzin, 5′‐caffeoylquinic acid) that can help in …
polyphenols (eg, procyanidins, phloridzin, 5′‐caffeoylquinic acid) that can help in …
Targeting glucose transporters for breast cancer therapy: the effect of natural and synthetic compounds
AM Barbosa, F Martel - Cancers, 2020 - mdpi.com
Reprogramming of cellular energy metabolism is widely accepted to be a cancer hallmark.
The deviant energetic metabolism of cancer cells-known as the Warburg effect-consists in …
The deviant energetic metabolism of cancer cells-known as the Warburg effect-consists in …