Background Drug safety has the highest priority in the treatment of pregnant women, as any
effect on fetal development will not be immediately evident, and the harm that ensues may …

Acute kidney injury (AKI) is a common problem in the neonatal intensive care unit (NICU).
Neonates born at< 1,000 g (extremely low birth weight, ELBW) are at an increased risk of …

Objective To evaluate the effectiveness of drugs used to constrict patent ductus arteriosus
(PDA) in newborns< 28 weeks. Methods We performed a secondary analysis of the multi …

Background Patent ductus arteriosus (PDA) is associated with significant morbidity and
mortality in preterm infants. Several non‐pharmacological, pharmacological, and surgical …

Background: Indomethacin and ibuprofen, two commonly used prostaglandin inhibitors, are
the drugs of choice for patent ductus arteriosus. However, paracetamol is an alternative …

No consensus has been reached on which patent ductus arteriosus (PDAs) in preterm
infants require treatment and if so, how, and when they should be treated. A prospective …

Background/Aims: Nasal continuous positive airway pressure (nCPAP) was recommended
as the initial respiratory support for spontaneous breathing in infants with very low birth …

Paracetamol (acetaminophen) has been proposed as an alternative medication for closing
hemodynamically significant patent ductus arteriosus (PDA). However, the clinical outcomes …

Objective Evaluate predictors of successful PDA closure following acetaminophen treatment.
Study design Retrospective cohort study of≤ 30 weeks GA infants born from 1 January 2013 …

Aim Ibuprofen and indomethacin are the preferred drug treatment for patent ductus
arteriosus (PDA) in preterm neonates. The comparative safety and efficacy of paracetamol …