[HTML][HTML] Oxidative stress as a crucial factor in liver diseases

H Cichoż-Lach, A Michalak - World journal of gastroenterology …, 2014 - ncbi.nlm.nih.gov
Redox state constitutes an important background of numerous liver disorders. The redox
state participates in the course of inflammatory, metabolic and proliferative liver diseases …

[HTML][HTML] The role of amino acids in neurotransmission and fluorescent tools for their detection

R Dalangin, A Kim, RE Campbell - International journal of molecular …, 2020 - mdpi.com
Neurotransmission between neurons, which can occur over the span of a few milliseconds,
relies on the controlled release of small molecule neurotransmitters, many of which are …

[HTML][HTML] Gut microbiota changes in the extreme decades of human life: a focus on centenarians

A Santoro, R Ostan, M Candela, E Biagi… - Cellular and Molecular …, 2018 - Springer
The gut microbiota (GM) is a complex, evolutionarily molded ecological system, which
contributes to a variety of physiological functions. The GM is highly dynamic, being sensitive …

Hydrogen-rich saline attenuated subarachnoid hemorrhage-induced early brain injury in rats by suppressing inflammatory response: possible involvement of NF-κB …

A Shao, H Wu, Y Hong, S Tu, X Sun, Q Wu… - Molecular …, 2016 - Springer
Early brain injury (EBI), highlighted with inflammation and apoptosis, occurring within 72 h
after subarachnoid hemorrhage (SAH), is associated with the prognosis of SAH. Recent …

[HTML][HTML] The interrelation between reactive oxygen species and autophagy in neurological disorders

C Fang, L Gu, D Smerin, S Mao, X Xiong - Oxidative Medicine and …, 2017 - hindawi.com
Neurological function deficits due to cerebral ischemia or neurodegenerative diseases such
as Alzheimer's disease (AD) and Parkinson's disease (PD) have long been considered a …

[HTML][HTML] Propionate and Alzheimer's disease

J Killingsworth, D Sawmiller, RD Shytle - Frontiers in aging …, 2021 - frontiersin.org
Propionate, a short-chain fatty acid, serves important roles in the human body. However, our
review of the current literature suggests that under certain conditions, excess levels of …

Changes in the mitochondrial antioxidant systems in neurodegenerative diseases and acute brain disorders

J Ruszkiewicz, J Albrecht - Neurochemistry international, 2015 - Elsevier
Oxidative and nitrosative stress (ONS) contributes to the pathogenesis of most brain
maladies, and the magnitude of ONS is related to the ability of cellular antioxidants to …

[HTML][HTML] Overview of oxidative stress findings in hepatic encephalopathy: From cellular and ammonium-based animal models to human data

D Simicic, C Cudalbu, K Pierzchala - Analytical Biochemistry, 2022 - Elsevier
Oxidative stress is a natural phenomenon in the body. Under physiological conditions
intracellular reactive oxygen species (ROS) are normal components of signal transduction …

Protective role of chrysin on thioacetamide-induced hepatic encephalopathy in rats

SA El-Marasy, SA El Awdan… - Chemico-Biological …, 2019 - Elsevier
Hepatic encephalopathy (HE) is a serious neuropsychiatric syndrome due to either acute or
chronic hepatic failure. This study aimed to investigate the possible neuroprotective effect of …

[HTML][HTML] How glutamate is managed by the blood–brain barrier

RA Hawkins, JR Viña - Biology, 2016 - mdpi.com
A facilitative transport system exists on the blood–brain barrier (BBB) that has been tacitly
assumed to be a path for glutamate entry to the brain. However, glutamate is a non-essential …