Placental origins of chronic disease
Epidemiological evidence links an individual's susceptibility to chronic disease in adult life to
events during their intrauterine phase of development. Biologically this should not be …
events during their intrauterine phase of development. Biologically this should not be …
Placental responses to changes in the maternal environment determine fetal growth
KG Dimasuay, P Boeuf, TL Powell… - Frontiers in physiology, 2016 - frontiersin.org
Placental responses to maternal perturbations are complex and remain poorly understood.
Altered maternal environment during pregnancy such as hypoxia, stress, obesity, diabetes …
Altered maternal environment during pregnancy such as hypoxia, stress, obesity, diabetes …
Management and feeding strategies in early life to increase piglet performance and welfare around weaning: A review
Simple Summary Weaning is an important period for the swine industry and is influenced by
the early events that occur during gestation and lactation. Therefore, a range of dietary and …
the early events that occur during gestation and lactation. Therefore, a range of dietary and …
Placenta-on-a-chip: a novel platform to study the biology of the human placenta
Objective: Studying the biology of the human placenta represents a major experimental
challenge. Although conventional cell culture techniques have been used to study different …
challenge. Although conventional cell culture techniques have been used to study different …
[HTML][HTML] Placental energy metabolism in health and disease—significance of development and implications for preeclampsia
ILMH Aye, CE Aiken, DS Charnock-Jones… - American journal of …, 2022 - Elsevier
The placenta is a highly metabolically active organ fulfilling the bioenergetic and
biosynthetic needs to support its own rapid growth and that of the fetus. Placental metabolic …
biosynthetic needs to support its own rapid growth and that of the fetus. Placental metabolic …
Placental nutrient transport and intrauterine growth restriction
F Gaccioli, S Lager - Frontiers in physiology, 2016 - frontiersin.org
Intrauterine growth restriction refers to the inability of the fetus to reach its genetically
determined potential size. Fetal growth restriction affects approximately 5–15% of all …
determined potential size. Fetal growth restriction affects approximately 5–15% of all …
Adiponectin supplementation in pregnant mice prevents the adverse effects of maternal obesity on placental function and fetal growth
Mothers with obesity or gestational diabetes mellitus have low circulating levels of
adiponectin (ADN) and frequently deliver large babies with increased fat mass, who are …
adiponectin (ADN) and frequently deliver large babies with increased fat mass, who are …
Placental transporter localization and expression in the human: the importance of species, sex, and gestational age differences
N Walker, P Filis, U Soffientini… - Biology of …, 2017 - academic.oup.com
The placenta is a critical organ during pregnancy, essential for the provision of an optimal
intrauterine environment, with fetal survival, growth, and development relying on correct …
intrauterine environment, with fetal survival, growth, and development relying on correct …
Role of placental nutrient sensing in developmental programming
Altered maternal nutrition and metabolism, restricted utero-placental blood flow, and other
perturbations in the maternal compartment may disturb critical periods of fetal development …
perturbations in the maternal compartment may disturb critical periods of fetal development …
The role of placental nutrient sensing in maternal-fetal resource allocation
The placenta mediates maternal-fetal exchange and has historically been regarded as a
passive conduit for nutrients. However, emerging evidence suggests that the placenta …
passive conduit for nutrients. However, emerging evidence suggests that the placenta …