Next-generation sequencing: advances and applications in cancer diagnosis
S Serratì, S De Summa, B Pilato, D Petriella… - OncoTargets and …, 2016 - Taylor & Francis
Technological advances have led to the introduction of next-generation sequencing (NGS)
platforms in cancer investigation. NGS allows massive parallel sequencing that affords …
platforms in cancer investigation. NGS allows massive parallel sequencing that affords …
Electrospun nanofibers for cancer diagnosis and therapy
The advent of nanotechnology has provided unprecedented opportunities for nanomedicine.
Electrospun nanofibers have some astounding features such as high loading capacity …
Electrospun nanofibers have some astounding features such as high loading capacity …
Current molecular-targeted therapies in NSCLC and their mechanism of resistance
Z Schrank, G Chhabra, L Lin, T Iderzorig, C Osude… - Cancers, 2018 - mdpi.com
Lung cancer is treated with many conventional therapies, such as surgery, radiation, and
chemotherapy. However, these therapies have multiple undesirable side effects. To bypass …
chemotherapy. However, these therapies have multiple undesirable side effects. To bypass …
[HTML][HTML] Gene mutations and actionable genetic lesions in mantle cell lymphoma
Mutations and epigenetic alterations are key events in transforming normal cells to cancer
cells. Mantle cell lymphoma (MCL), a non-Hodgkin's lymphoma of the B-cell, is an …
cells. Mantle cell lymphoma (MCL), a non-Hodgkin's lymphoma of the B-cell, is an …
Glycosaminoglycans and glycolipids as potential biomarkers in lung cancer
In this report, we used liquid chromatography-mass spectrometry and Western blotting to
analyze the content and structure of glycosaminoglycans, glycolipids and selected proteins …
analyze the content and structure of glycosaminoglycans, glycolipids and selected proteins …
Biomolecular analysis of matrix proteoglycans as biomarkers in non small cell lung cancer
MP Rangel, VK de Sá, T Prieto, JRM Martins… - Glycoconjugate …, 2018 - Springer
Matrix proteoglycans (PGs) have shown promise as biomarker in malignancies. We
employed agarose gel eletrophoresis, quantitative real-time reverse transcription …
employed agarose gel eletrophoresis, quantitative real-time reverse transcription …
Next-Generation Sequencing and Quantitative Proteomics of Hutchinson-Gilford progeria syndrome-derived cells point to a role of nucleotide metabolism in premature …
J Mateos, J Fafian-Labora, M Morente-Lopez… - PLoS …, 2018 - journals.plos.org
Hutchinson-Gilford progeria syndrome (HGPS) is a very rare fatal disease characterized for
accelerated aging. Although the causal agent, a point mutation in LMNA gene, was …
accelerated aging. Although the causal agent, a point mutation in LMNA gene, was …
KRAS and the reality of personalized medicine in non-small cell lung cancer
Lung cancer is the leading cause of mortality among all cancer types worldwide. The latest
available global statistics of the World Health Organization report 1.59 million casualities in …
available global statistics of the World Health Organization report 1.59 million casualities in …
[PDF][PDF] Research progress on antioxidant activity of natural products
L Chen, X Zhang, T Hao, R Liang… - European Journal of …, 2016 - biomedicaljour.com
Natural or synthesized antioxidants are compounds that can inhibit or delay the onset
oxidation. Due to the wide availability of natural antioxidants and the increasing concerns on …
oxidation. Due to the wide availability of natural antioxidants and the increasing concerns on …
The genome-wide DNA sequence specificity of the anti-tumour drug bleomycin in human cells
The cancer chemotherapeutic agent, bleomycin, cleaves DNA at specific sites. For the first
time, the genome-wide DNA sequence specificity of bleomycin breakage was determined in …
time, the genome-wide DNA sequence specificity of bleomycin breakage was determined in …