Gadolinium-based contrast agents (GBCAs) are commonly used for enhancement in MR
imaging and have long been considered safe when administered at recommended doses …

In recent years, the existence of a mass transport system in the brain via cerebrospinal fluid
(CSF) or interstitial fluid (ISF) has been suggested by many studies. The glymphatic system …

Purpose The diffusion tensor image analysis along the perivascular space (DTI-ALPS)
method was developed to evaluate the brain's glymphatic function or interstitial fluid …

Purpose The activity of the glymphatic system is impaired in animal models of Alzheimer's
disease (AD). We evaluated the activity of the human glymphatic system in cases of AD with …

Objective To assess the glymphatic activity in patients with idiopathic normal pressure
hydrocephalus (NPH) using the “Diffusion Tensor Image-Analysis aLong the Perivascular …

Objective Multiple clinical and preclinical studies have reported a signal intensity increase
and the presence of gadolinium (Gd) in the brain after repeated administration of Gd-based …

For magnetic resonance, the established class of intravenous contrast media is the
gadolinium-based contrast agents. In the 3 decades since initial approval, these have …

Objective: We aimed to evaluate the activity of the human glymphatic system in type 2
diabetes mellitus (T2DM) using diffusion tensor image analysis along with the perivascular …

The central nervous system (CNS) was previously thought to be the only organ system
lacking lymphatic vessels to remove waste products from the interstitial space. Recently …

In recent years, gadolinium-based contrast agents have been associated with different types
of toxicity. In particular, nephrogenic systemic fibrosis, a progressive sclerotic …