Vitreous and vision degrading myodesopsia
J Sebag - Progress in Retinal and Eye Research, 2020 - Elsevier
Macromolecules comprise only 2% of vitreous, yet are responsible for its gel state,
transparency, and physiologic function (s) within the eye. Myopia and aging alter collagen …
transparency, and physiologic function (s) within the eye. Myopia and aging alter collagen …
Vitreous humor: composition, characteristics and implication on intravitreal drug delivery
Purpose: Intravitreal administration of drug molecules is one of the most common routes for
treating posterior segment eye diseases. However, the properties of vitreous humour …
treating posterior segment eye diseases. However, the properties of vitreous humour …
[HTML][HTML] The genetics and disease mechanisms of rhegmatogenous retinal detachment
BM Govers, RAC van Huet, S Roosing, S Keijser… - Progress in Retinal and …, 2023 - Elsevier
Rhegmatogenous retinal detachment (RRD) is a sight threatening condition that warrants
immediate surgical intervention. To date, 29 genes have been associated with monogenic …
immediate surgical intervention. To date, 29 genes have been associated with monogenic …
Synthesis and characterization of a lubricin mimic (mLub) to reduce friction and adhesion on the articular cartilage surface
The lubricating proteoglycan, lubricin, facilitates the remarkable low friction and wear
properties of articular cartilage in the synovial joints of the body. Lubricin lines the joint …
properties of articular cartilage in the synovial joints of the body. Lubricin lines the joint …
Macro-and microscale properties of the vitreous humor to inform substitute design and intravitreal biotransport
NK Tram, CJ Maxwell, KE Swindle-Reilly - Current Eye Research, 2021 - Taylor & Francis
Research on the vitreous humor and development of hydrogel vitreous substitutes have
gained a rapid increase in interest within the past two decades. However, the properties of …
gained a rapid increase in interest within the past two decades. However, the properties of …
Mendelian randomization study confirms causal relationship between myopia and vitreous disorders
J Xu, Y Mo - BMC Medical Genomics, 2023 - Springer
Purpose This study aims to investigate the potential bidirectional causal relationship
between myopia and vitreous disorders from a genetic perspective, as vitreous disorders …
between myopia and vitreous disorders from a genetic perspective, as vitreous disorders …
Glycosaminoglycan and proteoglycan biotherapeutics in articular cartilage protection and repair strategies: novel approaches to visco‐supplementation in …
The aim of this study is to review developments in glycosaminoglycan and proteoglycan
research relevant to cartilage repair biology and in particular the treatment of osteoarthritis …
research relevant to cartilage repair biology and in particular the treatment of osteoarthritis …
Proteoglycans and proteoglycan mimetics for tissue engineering
Proteoglycans play a crucial role in proper tissue morphology and function throughout the
body that is defined by a combination of their core protein and the attached …
body that is defined by a combination of their core protein and the attached …
Effects of enzymatic degradation on dynamic mechanical properties of the vitreous and intravitreal nanoparticle mobility
Intravitreal mobility of nanocarriers may have implications on the efficacy of the
encapsulated drug in the treatment of vitreo-retinal diseases, with any changes in the …
encapsulated drug in the treatment of vitreo-retinal diseases, with any changes in the …
Biomimetic strategies for the deputization of proteoglycan functions
Proteoglycans (PGs), which have glycosaminoglycan chains attached to their protein cores,
are essential for maintaining the morphology and function of healthy body tissues …
are essential for maintaining the morphology and function of healthy body tissues …