MicroRNA profiling: approaches and considerations
CC Pritchard, HH Cheng, M Tewari - Nature Reviews Genetics, 2012 - nature.com
MicroRNAs (miRNAs) are small RNAs that post-transcriptionally regulate the expression of
thousands of genes in a broad range of organisms in both normal physiological contexts …
thousands of genes in a broad range of organisms in both normal physiological contexts …
Extracellular vesicles from red blood cells and their evolving roles in health, coagulopathy and therapy
Red blood cells (RBCs) release extracellular vesicles (EVs) including both endosome-
derived exosomes and plasma-membrane-derived microvesicles (MVs). RBC-derived EVs …
derived exosomes and plasma-membrane-derived microvesicles (MVs). RBC-derived EVs …
A one-pot isothermal Cas12-based assay for the sensitive detection of microRNAs
The use of microRNAs as clinical cancer biomarkers is hindered by the absence of accurate,
fast and inexpensive assays for their detection in biofluids. Here we report a one-step and …
fast and inexpensive assays for their detection in biofluids. Here we report a one-step and …
Exosomal microRNA signatures in multiple sclerosis reflect disease status
Multiple Sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system (CNS). There is currently no single definitive test for MS. Circulating …
nervous system (CNS). There is currently no single definitive test for MS. Circulating …
Body fluid biomarkers in multiple sclerosis
M Comabella, X Montalban - The Lancet Neurology, 2014 - thelancet.com
Biomarkers can be thought of as multifaceted indicators of healthy status or of pathological
disorders. The study of multiple sclerosis can benefit from the use of biomarkers because of …
disorders. The study of multiple sclerosis can benefit from the use of biomarkers because of …
Circulating microRNAs as biomarkers for disease staging in multiple sclerosis
Objective MicroRNAs (miRNAs) are single‐stranded, small noncoding RNAs that regulate
gene expression. Because they are stable in serum, they are being developed as …
gene expression. Because they are stable in serum, they are being developed as …
Exosome‐encapsulated microRNAs as circulating biomarkers for breast cancer
Breast cancer is a highly prevalent disease, accounting for 29% of invasive cancers in
women. Survival from this disease depends on the stage at diagnosis, with patients who are …
women. Survival from this disease depends on the stage at diagnosis, with patients who are …
miR‐155 as a multiple sclerosis–relevant regulator of myeloid cell polarization
CS Moore, VTS Rao, BA Durafourt… - Annals of …, 2013 - Wiley Online Library
Objective To define the functional significance of increased miR‐155 expression in myeloid
cells in multiple sclerosis (MS). Methods miR‐155 expression levels were measured in …
cells in multiple sclerosis (MS). Methods miR‐155 expression levels were measured in …
[HTML][HTML] MicroRNA: key gene expression regulators
MicroRNAs, also called miRNAs, are small 19–22 nucleotide (nt) sequences of noncoding
RNA that work as endogenous epigenetic gene expression regulators. They are transcribed …
RNA that work as endogenous epigenetic gene expression regulators. They are transcribed …
Exosome‐associated miRNA profile as a prognostic tool for therapy response monitoring in multiple sclerosis patients
I Manna, E Iaccino, V Dattilo, S Barone… - The FASEB …, 2018 - Wiley Online Library
Multiple sclerosis (MS) is an autoimmune pathology leading to neurodegeneration. Because
of the complexity and heterogenic etiology of this disease, diagnosis and treatment for …
of the complexity and heterogenic etiology of this disease, diagnosis and treatment for …