A beginner's guide to rigor and reproducibility in fluorescence imaging experiments

JY Lee, M Kitaoka - Molecular Biology of the Cell, 2018 - Am Soc Cell Biol
Fluorescence light microscopy is an indispensable approach for the investigation of cell
biological mechanisms. With the development of cutting-edge tools such as genetically …

tRNA Analysis of eXpression (tRAX): A tool for integrating analysis of tRNAs, tRNA-derived small RNAs, and tRNA modifications

AD Holmes, JM Howard, PP Chan, TM Lowe - Biorxiv, 2022 - biorxiv.org
Recent high-throughput sequencing protocols have facilitated increased accuracy in
measurements of transfer tRNAs (tRNAs) and tRNA-derived small RNAs (tDRs) from …

SRSF6 regulates alternative splicing of genes involved in DNA damage response and DNA repair in HeLa cells

X Yang, P Zhan, S Feng, H Ji, W Tian… - Oncology …, 2020 - spandidos-publications.com
Alternative splicing (AS) occurs in nearly all human genes and abnormal AS has a close
association with cancer. Serine and arginine‑rich splicing factor 6 (SRSF6), a canonical …

Strategy for RNA-seq experimental design and data analysis

G Gimenez, PA Stockwell, EJ Rodger… - Oral Biology: Molecular …, 2022 - Springer
Ribonucleic acids (RNAs) are fundamental molecules that control regulation and expression
of the genome and therefore the function of a cell. Robust analysis and quantification of RNA …

The graph rubric: Development of a teaching, learning, and research tool

A Angra, SM Gardner - CBE—Life Sciences Education, 2018 - Am Soc Cell Biol
As undergraduate biology curricula increasingly aim to provide students with access to
courses and experiences that engage them in the practices of science, tools are needed for …

Reproducibility blues

B Pulverer - The EMBO journal, 2015 - embopress.org
Research findings advance science only if they are significant, reliable and reproducible.
Scientists and journals must publish robust data in a way that renders it optimally …

Uptake and impact of silver nanoparticles on the growth of an estuarine dinoflagellate, Prorocentrum minimum

SV Butz, JL Pinckney, SC Apte, JR Lead - NanoImpact, 2019 - Elsevier
Silver nanoparticles (AgNPs) are widely used and have been shown to have relatively high
inherent toxicity to a range of living organisms including fish, annelids, daphnia and algae …

Analysis method of cellular stress caused by intermediate dose‐rate irradiation using a cell lysate array technique

N Morishima, H Ogata, J Magae, Y Ito… - Genes to …, 2023 - Wiley Online Library
Ionizing radiation damages DNA and may lead to the development of cancer. Irradiation
also generates reactive oxygen species (ROS) which cause damage to various biological …

Statistical relevance—relevant statistics, part II: presenting experimental data

B Klaus - The EMBO Journal, 2016 - embopress.org
In the first part of this article series, I discussed general guidelines for analyzing the results of
scientific experiments (Klaus, 2015). The next step is the graphical representation of the …

Stakeholders Experiences on Social and Emotional Impact of Remote Learning: A Qualitative Narrative Inquiry Study

T Huynh - 2024 - search.proquest.com
COVID-19 impacted students due to the rapid shift to online learning. In response to health
and safety concerns, schools faced disruptions to the learning environment and ultimately …