The human immunodeficiency virus (HIV) is responsible for acquired immune deficiency
syndrome (AIDS), one of the major pandemic diseases. Highly active antiretroviral therapy …

Acquired immunodeficiency syndrome (AIDS), caused by the human immunodeficiency
virus (HIV), is one of the leading causes of human deaths. The advent of different anti-HIV …

Malaria, caused by the genus Plasmodium, remains a global public health concern. It is
estimated by the World Health Organization that over 40% of the world's population lives in …

Abstract A series of 1, 2, 3‐triazol‐1‐ylbenzenesulfonamide derivatives was designed,
synthesized and their ability to inhibit several carbonic anhydrase isoforms was evaluated …

A series of 4-phenylcoumarin derivatives was synthesized and evaluated for their cellular
anti-HIV-1 and HIV-2 activities as well as their inhibitory effects against HIV-1 reverse …

Indole is known as a versatile heterocyclic building block for its multiple pharmacological
activities and has a high probability of success in the race for drug candidates. Many natural …

Acquired immune deficiency syndrome (AIDS) mainly caused by human immunodeficiency
virus (HIV) type 1 (HIV-1) is a deadliest infectious disease, in which the immune system …

Abstract 1 H-Indole-3-carbaldehyde and related members of the indole family are ideal
precursors for the synthesis of active molecules. 1 H-Indole-3-carbaldehyde and its …

The primary focus of bisphosphonate medications is on targeting human farnesyl
pyrophosphate synthase (hFPPS), an essential regulator of mammalian isoprenoids. Yet …

Microtubules and the mitotic spindle have become an important target for cancer treatment
due to their critical role in cell division. In this work, a novel series of benzofuran and indole …