Sesamol, a major lignan in sesame seeds (Sesamum indicum): Anti-cancer properties and mechanisms of action

AF Majdalawieh, ZR Mansour - European journal of pharmacology, 2019 - Elsevier
Sesamol is a natural phenolic compound and a major lignan isolated from sesame seeds
(Sesamum indicum) and sesame oil. The therapeutic potential of sesamol was investigated …

Herb and spices in colorectal cancer prevention and treatment: A narrative review

MS Hossain, MA Kader, KW Goh, M Islam… - Frontiers in …, 2022 - frontiersin.org
Colorectal cancer (CRC) is the second most deadly cancer worldwide. CRC management is
challenging due to late detection, high recurrence rate, and multi-drug resistance. Herbs and …

Sesamol: A powerful functional food ingredient from sesame oil for cardioprotection

P Jayaraj, CA Narasimhulu, S Rajagopalan… - Food & function, 2020 - pubs.rsc.org
Phytophenols are important bioactive food based chemical entities, largely present in
several natural sources. Among them, sesamol is one of the key natural phenols found in …

Sesamol-loaded solid lipid nanoparticles for treatment of skin cancer

T Geetha, M Kapila, O Prakash, PK Deol… - Journal of drug …, 2015 - Taylor & Francis
Role of reactive oxygen species (ROS) in skin carcinogenesis is well documented. Natural
molecules, like sesamol, with marked antioxidant potential can be useful in combating skin …

[HTML][HTML] Antioxidant, lipid lowering, and membrane stabilization effect of sesamol against doxorubicin-induced cardiomyopathy in experimental rats

A Chennuru, MTS Saleem - BioMed research international, 2013 - hindawi.com
The present study was designed to evaluate the cardioprotective effect of sesamol against
doxorubicin-induced cardiomyopathy in rats. In this study, the cardioprotective effect of …

[HTML][HTML] Sesamol Protects Testis from Ischemia-Reperfusion Injury through Scavenging Reactive Oxygen Species and Upregulating CREMτ Expression

SM Wei, RY Wang, YS Chen - Oxidative Medicine and Cellular …, 2020 - hindawi.com
Testicular torsion/detorsion-induced damage is considered as a typical ischemia-
reperfusion injury attributed to excessive reactive oxygen species (ROS) production. ROS …

Cyclodextrin decorated nanosponges of sesamol: Antioxidant, anti-tyrosinase and photostability assessment

B Gupta, P Dalal, R Rao - Food Bioscience, 2021 - Elsevier
Sesamol (SES), a natural phenolic bioactive, is endowed with benefits in food and
pharmaceuticals. However, its utility is compromised by certain unfavorable …

Nephroprotective effect of green tea, rosmarinic acid and rosemary on N-diethylnitrosamine initiated and ferric nitrilotriacetate promoted acute renal toxicity in Wistar …

MA El-Desouky, MH Mahmoud, BY Riad… - Interdisciplinary …, 2019 - sciendo.com
The present study was designed to investigate the chemoprotective effect of green tea
extract (GTE), rosmarinic acid (RA) and rosemary extract (RE) against diethylnitrosamine …

Biopharmaceutical profiling of sesamol: physiochemical characterization, gastrointestinal permeability and pharmacokinetic evaluation

T Geetha, N Singh, PK Deol, IP Kaur - RSC advances, 2015 - pubs.rsc.org
Sesamol has been studied extensively in the past two decades for its curative role in various
diseases owing to its antioxidant potential. In vitro and in vivo pre-clinical studies indicate …

Stimulation of gene expression and activity of antioxidant related enzyme in Sprague Dawley rat kidney induced by long-term iron toxicity

H Budak, EF Kocpinar, N Gonul, H Ceylan… - … and Physiology Part C …, 2014 - Elsevier
The trace elements such as iron are vital for various enzyme activities and for other cellular
proteins, but iron toxicity causes the production of reactive oxygen species (ROS) that …