There has been extensive progress in understanding the cellular and molecular
mechanisms of inflammation and immune regulation in allergic diseases of the skin and …

Skin barrier dysfunction, a defining feature of atopic dermatitis (AD), arises from multiple
interacting systems. In AD, skin inflammation is caused by host–environment interactions …

The discovery in 2006 that loss-of-function mutations in the filaggrin gene (FLG) cause
ichthyosis vulgaris and can predispose to atopic dermatitis (AD) galvanized the dermatology …

The skin barrier is an important shield regulating the outside‐in as well as inside‐out
penetration of water, nutrients, ions and environmental stimuli. We can distinguish four …

Atopic dermatitis (AD) is a chronic inflammatory skin disease presenting with recurrent
eczematous lesions and intense pruritus. It is common and affects both children and adults …

Abstract Purpose of Review Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin
disorder that is a major public health burden worldwide. AD lesions are often colonized by …

Candida albicans (C. albicans) infection is a potential complication in the individuals with
atopic dermatitis (AD) and can affect clinical course of the disease. Here, using primary …

Filaggrin (FLG) protein is indispensable for multiple aspects of the epidermal barrier function
but its accumulation in a monomeric filaggrin form may initiate premature keratinocytes …

Staphylococcus aureus is a key pathogen in atopic dermatitis (AD) pathogenicity. Over half
of AD patients are carriers of S. aureus. Clinical isolates derived from AD patients produce …

Background Eczema is a chronic inflammatory disease associated with impaired quality of
life. We identified indoor environmental risk factors, to provide strong evidence for the …