Astronaut omics and the impact of space on the human body at scale
Future multi-year crewed planetary missions will motivate advances in aerospace nutrition
and telehealth. On Earth, the Human Cell Atlas project aims to spatially map all cell types in …
and telehealth. On Earth, the Human Cell Atlas project aims to spatially map all cell types in …
Impact of Microgravity and Other Spaceflight Factors on Retina of Vertebrates and Humans In Vivo and In Vitro
EN Grigoryan - Life, 2023 - mdpi.com
Spaceflight (SF) increases the risk of developmental, regenerative, and physiological
disorders in animals and humans. Astronauts, besides bone loss, muscle atrophy, and …
disorders in animals and humans. Astronauts, besides bone loss, muscle atrophy, and …
Spatially resolved multiomics on the neuronal effects induced by spaceflight in mice
Y Masarapu, E Cekanaviciute, Z Andrusivova… - Nature …, 2024 - nature.com
Impairment of the central nervous system (CNS) poses a significant health risk for astronauts
during long-duration space missions. In this study, we employed an innovative approach by …
during long-duration space missions. In this study, we employed an innovative approach by …
Harmonizing heterogeneous transcriptomics datasets for machine learning-based analysis to identify spaceflown murine liver-specific changes
NASA has employed high-throughput molecular assays to identify sub-cellular changes
impacting human physiology during spaceflight. Machine learning (ML) methods hold the …
impacting human physiology during spaceflight. Machine learning (ML) methods hold the …
Physical exercise restores adult neurogenesis deficits induced by simulated microgravity
A Gros, FM Furlan, V Rouglan, A Favereaux… - npj …, 2024 - nature.com
Cognitive impairments have been reported in astronauts during spaceflights and
documented in ground-based models of simulated microgravity (SMG) in animals. However …
documented in ground-based models of simulated microgravity (SMG) in animals. However …
Thermal inkjet makes label-free single-cell proteomics accessible and easy
S Stanisheuski, A Ebrahimi, KA Vaidya… - Frontiers in …, 2024 - frontiersin.org
In this study, we adapted an HP D100 Single Cell Dispenser–a novel low-cost thermal inkjet
(TIJ) platform with impedance-based single cell detection–for dispensing of individual cells …
(TIJ) platform with impedance-based single cell detection–for dispensing of individual cells …
Establishing a method for the cryopreservation of viable peripheral blood mononuclear cells in the International Space Station
H Ishii, R Endo, S Hamanaka, N Hidaka, M Miyauchi… - npj …, 2024 - nature.com
The analysis of cells frozen within the International Space Station (ISS) will provide crucial
insights into the impact of the space environment on cellular functions and properties. The …
insights into the impact of the space environment on cellular functions and properties. The …
Spatially resolved multiomics on the neuronal effects induced by spaceflight
Y Masarapu, E Cekanaviciute, Z Andrusivova… - 2023 - researchsquare.com
Impairment of the central nervous system (CNS) functions in astronauts is a major health risk
for long-duration space missions. Here, for the first time, we combine single-cell multiomics …
for long-duration space missions. Here, for the first time, we combine single-cell multiomics …
Enhancing European capabilities for application of multi-omics studies in biology and biomedicine space research
Following on from the NASA twins' study, there has been a tremendous interest in the use of
omics techniques in spaceflight. Individual space agencies, NASA's GeneLab, JAXA's …
omics techniques in spaceflight. Individual space agencies, NASA's GeneLab, JAXA's …