Aluminum-containing adjuvants have been used for over 90 years to enhance the immune
response to vaccines. Recent work has significantly advanced our understanding of the …

The majority of vaccines have been delivered into the muscular tissue. Skin contains large
amounts of antigen-presenting cells and has been recognized as a more immunogenic site …

Aluminium salts are by far the most commonly used adjuvants in vaccines. There are only
two aluminium salts which are used in clinically-approved vaccines, Alhydrogel® and …

Pyroptosis is a programmed cell death widely studied in cancer cells for tumour inhibition,
but rarely in dendritic cell (DC) activation for vaccine development. Here, we report the …

Adjuvants are important components in vaccines to increase the immunogenicity of proteins
and induce optimal immunity. In this study, we designed a novel ternary adjuvant system …

Aluminum‐containing adjuvants used in vaccine formulations suffer from low cellular
immunity, severe aggregation, and accumulation in the brain. Conventional aluminosilicates …

Autism spectrum disorder (ASD), schizophrenia, and bipolar disorder are genetically
complex and heterogeneous neurodevelopmental disorders (NDDs) resulting from genetic …

The use of vaccines including aluminum (Al)–based adjuvants is widespread among small
ruminants and other animals. They are associated with the appearance of transient injection …

Aluminum (Al) salts are commonly used as adjuvants in human and veterinary vaccines for
almost a century. Despite this long history of use and the very large number of exposed …

Aluminum-containing adjuvants are commonly used in vaccines to elicit an enhanced
immune response in patients. The structure and surface characteristics of aluminum …