Background In many countries of the industrialised world second generation ('atypical')
antipsychotics have become the first line drug treatment for people with schizophrenia. The …

Galactorrhea is commonly caused by hyperprolactinemia, especially when it is associated
with amenorrhea. Hyperprolactinemia is most often induced by medication or associated …

Background Different effectiveness profiles among antipsychotics may be a key point to
optimize treatment in patients suffering a first episode of psychosis to impact on long-term …

Background Amisulpride, aripiprazole, and olanzapine are first-line atypical antipsychotics
that have not previously been compared head-to-head in a pragmatic trial. We aimed to …

Background Assessment of suicide risk is crucial in schizophrenia and results concerning
risk contributed by hallucinations and persecutory delusions are inconsistent. We aimed to …

Background Inflammatory processes have been implicated in the etiology of schizophrenia
and related psychoses, in which cognitive deficits represent core symptoms. The aim of the …

Background Up to 75% of people with serious mental illness (SMI) such as schizophrenia
and bipolar disorder have co‐occurring substance use disorders (dual diagnosis). Dual …

Objective: The Positive and Negative Syndrome Scale is a primary outcome measure in
clinical trials examining the efficacy of antipsychotic medications. Although the Positive and …

An antidepressant carrier, mesoporous hydroxyapatite olanzapine (mesoHAP-OLZ), was
designed to maintain 3 weeks of constant medication release. The carrier was …

Objective: Akathisia is among the most unpleasant side effects related to antipsychotic drug
(AP) use, and possible associations between akathisia and agitation, depression and …