Airway remodeling in asthma: what really matters
Airway remodeling is generally quite broadly defined as any change in composition,
distribution, thickness, mass or volume and/or number of structural components observed in …
distribution, thickness, mass or volume and/or number of structural components observed in …
[HTML][HTML] The central role of IL-33/IL-1RL1 pathway in asthma: from pathogenesis to intervention
AKS Jayalatha, L Hesse, ME Ketelaar… - Pharmacology & …, 2021 - Elsevier
Abstract Interleukin-33 (IL-33), a member of the IL-1 family, and its cognate receptor,
Interleukin-1 receptor like-1 (IL-1RL1 or ST2), are susceptibility genes for childhood asthma …
Interleukin-1 receptor like-1 (IL-1RL1 or ST2), are susceptibility genes for childhood asthma …
Mechanisms of airway remodeling
N Hirota, JG Martin - Chest, 2013 - Elsevier
Airway remodeling comprises the structural changes of airway walls, induced by repeated
injury and repair processes. It is characterized by the changes of tissue, cellular, and …
injury and repair processes. It is characterized by the changes of tissue, cellular, and …
Remodeling in asthma
S Al-Muhsen, JR Johnson, Q Hamid - Journal of allergy and clinical …, 2011 - Elsevier
Airway remodeling encompasses the structural alterations in asthmatic compared with
normal airways. Airway remodeling in asthmatic patients involves a wide array of …
normal airways. Airway remodeling in asthmatic patients involves a wide array of …
Asthma: defining of the persistent adult phenotypes
SE Wenzel - The Lancet, 2006 - thelancet.com
The common disease asthma is probably not a single disease, but rather a complex of
multiple, separate syndromes that overlap. Although clinicians have recognised these …
multiple, separate syndromes that overlap. Although clinicians have recognised these …
Allergy diagnostic testing: an updated practice parameter
IL Bernstein, JT Li, DI Bernstein, R Hamilton… - Annals of allergy …, 2008 - annallergy.org
The major emphasis of this updated version of Practice Parameters for Allergy Diagnostic
Testing is focused on how technological refinements and their validations during the past …
Testing is focused on how technological refinements and their validations during the past …
The sentinel role of the airway epithelium in asthma pathogenesis
ST Holgate - Immunological reviews, 2011 - Wiley Online Library
The adoption of the concept that asthma is primarily a disease most frequently associated
with elaboration of T‐helper 2 (Th2)‐type inflammation has led to the widely held concept …
with elaboration of T‐helper 2 (Th2)‐type inflammation has led to the widely held concept …
NET balancing: a problem in inflammatory lung diseases
OZ Cheng, N Palaniyar - Frontiers in immunology, 2013 - frontiersin.org
Neutrophil extracellular traps (NETs) are beneficial antimicrobial defense structures that can
help fight against invading pathogens in the host. However, recent studies reveal that NETs …
help fight against invading pathogens in the host. However, recent studies reveal that NETs …
Epithelium dysfunction in asthma
ST Holgate - Journal of Allergy and Clinical Immunology, 2007 - Elsevier
Although asthma is an inflammatory disorder of the conducting airways involving TH2-type T
cells, there is increasing evidence for an important role played by the epithelium in …
cells, there is increasing evidence for an important role played by the epithelium in …
The mechanisms, diagnosis, and management of severe asthma in adults
ST Holgate, R Polosa - The Lancet, 2006 - thelancet.com
There has been a recent increase in the prevalence of asthma worldwide; however, the 5–
10% of patients with severe disease account for a substantial proportion of the health costs …
10% of patients with severe disease account for a substantial proportion of the health costs …