Reactive oxygen species signaling and oxidative stress: transcriptional regulation and evolution

Y Hong, A Boiti, D Vallone, NS Foulkes - Antioxidants, 2024 - mdpi.com
Since the evolution of the aerobic metabolism, reactive oxygen species (ROS) have
represented significant challenges to diverse life forms. In recent decades, increasing …

Zebrafish (Danio rerio) using as model for genotoxicity and DNA repair assessments: Historical review, current status and trends

A Canedo, TL Rocha - Science of the Total Environment, 2021 - Elsevier
Genotoxic pollutants lead to both DNA damage and changes in cell repair mechanisms.
Selecting suitable biomonitors is a fundamental step in genotoxicity studies. Thus, zebrafish …

Early-life lead exposure induces long-term toxicity in the central nervous system: From zebrafish larvae to juveniles and adults

Z Wang, H Zhao, Y Xu, J Zhao, Z Song, Y Bi, Y Li… - Science of the Total …, 2022 - Elsevier
Lead induced neurotoxicity has been extensively investigated. However, the potential
connections between early-life lead exposure and the frequently observed aberrant …

Developmental exposure to environmental levels of cadmium induces neurotoxicity and activates microglia in zebrafish larvae: From the perspectives of …

Y Xu, H Zhao, Z Wang, H Gao, J Liu, K Li, Z Song… - Chemosphere, 2022 - Elsevier
Cadmium (Cd) is a worldwide environmental pollutant that postures serious threats to
humans and ecosystems. Over the years, its adverse effects on the central nervous system …

Ferroptosis contributes to nickel-induced developmental neurotoxicity in zebrafish

Z Wang, K Li, Y Xu, Z Song, X Lan, C Pan… - Science of The Total …, 2023 - Elsevier
Nickel (Ni) is a widely utilized heavy metal that can cause environmental pollution and
health hazards. Its safety has attracted the attention of both the environmental ecology and …

Contrasting gene decay in subterranean vertebrates: insights from cavefishes and fossorial mammals

M Policarpo, J Fumey, P Lafargeas… - Molecular biology …, 2021 - academic.oup.com
Evolution sometimes proceeds by loss, especially when structures and genes become
dispensable after an environmental shift relaxes functional constraints. Subterranean …

Repeated evolution of circadian clock dysregulation in cavefish populations

KL Mack, JB Jaggard, JL Persons, EY Roback… - PLoS …, 2021 - journals.plos.org
Circadian rhythms are nearly ubiquitous throughout nature, suggesting they are critical for
survival in diverse environments. Organisms inhabiting largely arrhythmic environments …

Evolution shapes the gene expression response to oxidative stress

R Siauciunaite, NS Foulkes, V Calabrò… - International journal of …, 2019 - mdpi.com
Reactive oxygen species (ROS) play a key role in cell physiology and function. ROS
represents a potential source of damage for many macromolecules including DNA. It is …

Gadusol is a maternally provided sunscreen that protects fish embryos from DNA damage

MC Rice, JH Little, DL Forrister, J Machado, NL Clark… - Current Biology, 2023 - cell.com
Exposure to ultraviolet radiation (UVR) is harmful to living cells, leading organisms to evolve
protective mechanisms against UVR-induced cellular damage and stress. 1, 2 UVR …

Nickel oxide nanoparticles induce developmental neurotoxicity in zebrafish by triggering both apoptosis and ferroptosis

Z Wang, Y Bi, K Li, Z Song, C Pan, S Zhang… - Environmental …, 2023 - pubs.rsc.org
Nickel oxide nanoparticles (NiO-NPs) with unique characteristics have been widely utilized
in numerous manufacturing processes, which have inevitably led to environmental pollution …